Rengalin solution 100ml

Instruction for Rengalin solution

You can buy Rengalin solution on this page

Rengalin solution is a drug with an antitussive effect.

Release form and composition

Dosage forms of release:
    oral solution: colorless or almost colorless, transparent (10 ml in glass bottles, 1 bottle in a cardboard bundle).
Active substances in the composition of 1 tablet / 100 ml of solution:
    affinity purified antibodies to bradykinin - 6/120 mg;
    affinity purified antibodies to histamine - 6/120 mg;
    affinity purified antibodies to morphine - 6/120 mg.
Auxiliary components:
    100 ml of solution: anhydrous citric acid - 20 mg; maltitol - 6000 mg; potassium sorbate - 165 mg; glycerol - 3000 mg; purified water - up to 100 ml.

Pharmacodynamics

It has been experimentally proved that the components of solution Rengalin modify the activity of the ligand-receptor interaction of endogenous regulators with the corresponding receptors: antibodies to histamine - with H1-histamine receptors; to morphine - with opiate receptors; to bradykinin - with B1-receptors of bradykinin. The interaction of the active components of Rengalin in complex therapy enhances the antitussive effect.
In addition to the main drug, it has anti-edematous, anti-inflammatory, anti-allergic, analgesic (antibodies to morphine) and antispasmodic (antibodies to histamine and bradykinin) effects.
Due to the modification of histamine-dependent activation of H1 receptors and bradykinin-dependent activation of B1 receptors, the drug selectively reduces the excitability of the cough center of the medulla oblongata, and inhibits the central links of the cough reflex. Oppressing the centers of pain sensitivity in the thalamus, it blocks the transmission of pain impulses to the cerebral cortex. Due to the reduced release of plasma and tissue algogens, it inhibits the flow of pain impulses from the periphery.
Rengalin solution relieves local and systemic symptoms of allergic reactions, facilitates the course of acute pharyngitis, bronchitis and laryngitis, and reduces bronchospasm.

Pharmacokinetics

The study of the pharmacokinetics of the drug is not possible.

Indications for use

    diseases of the respiratory tract in acute and chronic course, occurring with bronchospasm and cough;
    unproductive / productive cough that accompanies influenza, acute respiratory viral infections, acute pharyngitis, laryngotracheitis, acute obstructive laryngitis, chronic bronchitis and other infectious and inflammatory and allergic diseases of the lower / upper respiratory tract.

Contraindications

Absolute:
    age up to 3 years;
    individual intolerance to the components of the drug.
Relative (diseases / conditions in which caution is required):
    diabetes mellitus (for solution);
    pregnancy and lactation.

Instructions for use Rengalin solution: method and dosage

Rengalin solution for cough is taken orally, preferably between meals.
For the maximum effect of the drug, tablets should be kept in the mouth until completely dissolved; the solution should be kept in the mouth before swallowing.
A single dose - 1 tablet or 5-10 ml of the solution, the frequency of administration - 3 times a day. During the first 3 days of therapy, the frequency of administration can be increased up to 4-6 times daily.
The duration of use is determined individually by the doctor and depends on the severity of the course of the disease.

Side effects

During the use of Rengalin solution from coughing, the development of reactions of increased individual sensitivity may be observed.

Overdose

The main symptoms of an overdose: dyspeptic symptoms, which are caused by the excipients that make up the drug.
Therapy: symptomatic.

special instructions

5 ml of the solution contains 0.3 g of maltitol, which corresponds to 0.02 XE (bread units). Maltitol metabolism requires insulin, although, due to its slow absorption in the gastrointestinal tract and hydrolysis, insulin is not needed.
The energy value of 1 teaspoon of the solution is ~ 1.37 kcal (5.7 kJ).
Doses of Rengalin solution to children are determined individually by the doctor.

Pregnancy and lactation

Due to the lack of clinical data confirming the safety / effectiveness of Rengalin solution during pregnancy and lactation, it is necessary to use the drug in this group of patients with caution after a careful assessment of the ratio of benefit to risk.

Use in childhood

According to the instructions, Rengalin solution for children can be used from the age of 3 years.

Drug interaction

To date, cases of incompatibility with other drugs / substances have not been reported.

Terms and conditions of storage

Store in a dark place at temperatures up to 25 ° C. Keep out of the reach of children.
Shelf life is 3 years.

Terms of sell

You don't need a prescription to buy Rengalin solution.