Magnerot tabs 500mg #50

User manual for Magnerot

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Magnerot is a magnesium-containing mineral supplement.

Release form and composition

Magnerot is produced in the form of tablets: round, flat, white, with a risk on one side and chamfers on both (10 pcs. In blisters, in a cardboard box 2 or 5 blisters).
Active ingredient: magnesium orotate dihydrate, in 1 tablet - 500 mg.
Excipients: sodium carmellose, povidone K30, microcrystalline cellulose, colloidal silicon dioxide, sodium cyclamate, magnesium stearate, lactose monohydrate, corn starch, talc.

Pharmacodynamics

Magnerot is a medicinal product that contains magnesium orotate as an active substance. Magnesium is an essential macronutrient required for many energy processes, involved in the metabolism of fats, carbohydrates, proteins and nucleic acids, as well as in the process of neuromuscular excitation (inhibits neuromuscular transmission).
Magnesium is a natural physiological calcium antagonist. It is necessary for the normal functioning of myocardial cells, since it takes part in its contractile function.
In stressful situations, the body loses large amounts of free ionized magnesium, so the additional intake of this macronutrient helps to increase resistance to stress.
Due to magnesium deficiency, it is possible to develop neuromuscular disorders (sensory and motor hyperexcitability, paresthesia, seizures), psychological changes (hallucinations, confusion, depression), cardiovascular diseases (tachycardia, ventricular extrasystole, hypersensitivity to cardiac glycosides). Lack of magnesium in pregnant women can lead to toxicosis and premature birth.
Magnerot contains magnesium in the form of orotat. Salts of orotic acid are involved in the metabolic process, they are necessary for the fixation of magnesium on the angiotensin-converting enzyme in the cell and for the manifestation of its action.

Pharmacokinetics

Approximately 35–40% of the dose taken is absorbed. The presence of salts of orotic acid in the composition of Magnerot contributes to the improvement of the absorption of magnesium.
Hypomagnesemia stimulates the absorption of magnesium ions.
The drug is excreted by the kidneys. Excretion increases with an excess of magnesium in the body and decreases with its deficiency.

Indications for use

Complex therapy and prevention:
    Angina pectoris;
    Arrhythmias (due to magnesium deficiency);
    Myocardial infarction;
    Chronic heart failure;
    Arteritis;
    Atherosclerosis;
    Spastic conditions - pain and muscle spasms (including angiospasm);
    Lipid metabolism disorders.

Contraindications

    Renal dysfunction;
    Liver cirrhosis with ascites;
    Predisposition to the formation of calcium-magnesium-ammonium-phosphate stones;
    Urolithiasis disease;
    Lactase deficiency, glucose-galactose malabsorption, lactose intolerance;
    Age under 18;
    Hypersensitivity to Magnerot's components.

Instructions for use of Magnerot: method and dosage

Magnerot should be taken orally with a small amount of liquid before meals.
In the first 7 days, 2 tablets are prescribed 3 times a day, then 1 tablet 2-3 times a day. The total duration of treatment is at least 4 weeks, if necessary, the drug can be taken for a long time.
With night cramps of the calf muscles, the drug is recommended to take 2-3 tablets in the evening.

Side effects

    Digestive system: when taking the drug in high doses - unstable stool, diarrhea (when the dose is reduced, they pass on their own);
    Others: allergic reactions.

Overdose

In patients with normal renal function, magnesium, when taken orally, does not cause the development of toxic reactions. Poisoning is possible with renal failure. The severity of the effects depends mainly on the concentration of magnesium in the blood serum. The main symptoms of an overdose: nausea, vomiting, slow reflexes, depression, anuric syndrome, respiratory depression, decreased blood pressure, coma, cardiac arrest.
Rehydration and forced diuresis are indicated as therapeutic measures. Patients with renal failure require hemodialysis or peritoneal dialysis.

Special instructions

It should be borne in mind that a lack of magnesium in the body can develop due to the following factors:
    Diseases of the gastrointestinal tract;
    Consuming foods low in magnesium;
    Taking certain medications (for example, diuretics, laxatives, oral contraceptives, glucocorticosteroids, cardiac glycosides, aminoglycoside antibiotics);
    Intense physical activity (due to increased sweating);
    Prolonged sun exposure;
    Conditions requiring an increased intake of magnesium, including pregnancy, lactation, stress, physical inactivity;
    Chronic alcoholism.
Magnerot does not have a negative effect on the speed of reactions and the ability to increase concentration of attention.

Application during pregnancy and lactation

During pregnancy and lactation, Magnerot can be used according to indications, since during these periods the need for magnesium increases significantly. If the content of this macronutrient is not balanced, serious complications may develop, including miscarriage.

Childhood use

According to the instructions, Magnerot is contraindicated for use in patients under the age of 18.

With impaired renal function

It is contraindicated to prescribe the drug to patients with impaired renal function and urolithiasis.

For violations of liver function

Magnerot is prohibited from admission for cirrhosis of the liver, accompanied by ascites (accumulation of fluid in the abdominal cavity).

Drug interactions

Glucocorticosteroids, muscle relaxants, oral contraceptives, insulin and diuretics reduce the effectiveness of Magnerot.
In the case of the simultaneous administration of iron preparations, tetracyclines or sodium fluoride, 2-3 hour intervals should be observed between medications. Magnerot may reduce their absorption.

Terms and conditions of storage

Keep out of reach of children at temperatures up to 25 ° C.
The shelf life is 5 years.

Reviews about Magnerot

In general, the reviews about Magnerot are positive. Patients note that the drug helps to get rid of cramps in the calf muscles, normalizes cardiac activity, eliminates the symptoms of arrhythmia (caused by a lack of magnesium), increases stress resistance, and relieves the tone of the uterus.
The disadvantages of many patients include only a fairly high cost of the drug, especially given the fact that the course of treatment in most cases is long and usually involves taking from 3 to 6 tablets per day.

Terms of sell

A prescription is not required to buy Magnerot.