Ekvator (Equator) tabs 10mg + 20mg #30

User manual for Ekvator

To buy Ekvator just add it to your shopping cart

Ekvator is a drug that lowers blood pressure.

Pharmacological properties

According to the instructions, the Ekvator is a combined agent, it contains amlodipine and lisinopril.
Lisinopril is an ACE inhibitor. Its mechanism of action is associated with blocking the conversion of angiotensin II from angiotensin I in the renal tissue. This reduces the effect of aldosterone on water metabolism, increases the formation of prostaglandins.
Lisinopril lowers blood pressure by vasodilation (arteries dilate more than veins) and a decrease in total peripheral vascular resistance (OPSS). In addition, its effect on the heart is expressed in the fact that:
    Reduced preload;
    The pressure in the pulmonary capillaries decreases;
    The resistance of the heart muscle to stress increases;
    The minute volume of blood flow increases.
Regular long-term use of the tablets improves the blood supply to the heart and reduces its hypertrophy. It has been proven that drugs from a number of ACE inhibitors prolong life in the presence of chronic heart failure, slow down the development of left ventricular dysfunction after myocardial infarction.
An additional effect of lisinopril is to reduce albuminuria, which makes it possible to recommend it when arterial hypertension is combined with diabetic nephropathy, but it does not affect the glucose level at all.
Amlodipine is the second constituent of the drug. This active ingredient is from the group of slow calcium channel blockers. Amlodipine reduces the transfer of calcium ions into the cells of smooth muscle fibers. Its effect on the cardiovascular system can be described as antianginal and antihypertensive. The principle of action of amlodipine in Ekvator tablets is similar to lisinopril - the systemic vascular resistance decreases and the blood supply to the myocardium improves.
The combination of two active agents in one preparation complements each other and eliminates unwanted side effects. So, calcium channel blockers usually retain water and sodium in the body, while ACE inhibitors, on the contrary, interfere with this process.
The action of the Ekvator according to the instructions begins in 1 hour, the maximum effect is visible 6 hours after administration. The therapeutic effect of the Ekvator, according to reviews, persists throughout the day.
With high blood pressure, the positive effect of the Ekvator according to the instructions is manifested in the first days of the beginning of its use; for a long-term permanent effect, it is necessary to take the drug constantly.
The drug is excreted unchanged; it does not turn into metabolites in the body.

Release form

Ekvator is released in tablets of 5 and 10 mg (for amlodipine).

Indications for use of Ekvator

The drug is prescribed if necessary for combination therapy in case of high blood pressure.

Contraindications

You can not use the Ekvator if you are intolerant to it and other ACE inhibitors, with stenosis (narrowing of the outlet) of the aorta and mitral valve in case of its hemodynamic significance.
Contraindications to taking Ekvator tablets will be hereditary and idiopathic angioedema, hypertrophic cardiomyopathy with obstruction, marked decrease in blood pressure (systolic pressure below 90 mm Hg), heart failure after myocardial infarction, unstable angina pectoris, cardiogenic shock, pregnancy and pregnancy ... Children under 18 years of age are not recommended to take Ekvator according to the instructions.
Caution in the use of Ekvator is required for bilateral renal artery stenosis, primary hyperaldosteronism, severe renal and hepatic dysfunction, after kidney transplantation, with hyperkalemia.

Instructions for use

The drug should be taken 1 time per day, in the morning, with water, without reference to food intake. In the initial period, the patient may be worried about a decrease in pressure while taking diuretics the day before, therefore, diuretics are canceled before starting treatment with the Ekvator 2 to 3 days.
If the use of diuretics is still necessary, the dose of the drug is reduced to 0.5 tablets. During the course of therapy, it is periodically required to monitor kidney function, potassium and sodium levels in the blood.

Side effects

According to reviews, the drug can sometimes give such undesirable reactions as headache, dizziness or coughing. They go away on their own and do not require discontinuation of the drug.

Terms of sell

You don't need a doctor's prescription to buy Ekvator.