Atoris tabs 20mg #90

Instruction for Atoris

Reed more and buy Atoris here

Release form and composition

The statin drug is marketed in the form of round biconvex tablets coated with a film-forming substance. At the fracture, their core has a dense structure, predominantly white.
Atoris is based on a potent substance - atorvastatin. Auxiliary components are lactose monohydrate, magnesium stearate, povidone, sodium lauryl sulfate, calcium carbonate and sodium croscarmellose.
Tablets are produced in dosages of 0.01 g, 0.02 g, 0.03 g, 0.04 g, 0.06 g and 0.08 g of atorvastatin. They are packaged in aluminum packages of 10 pieces and cardboard boxes of 1,3 or 9 blisters.

Pharmacological properties

Atoris is a statin drug that is a selective inhibitor of HMG-CoA reductase, the active enzymes of which are directly involved in the production of cholesterol in the liver. The main principle of action of atorvastatin is to suppress the vital activity of these enzymes and prevent their transformation into mevalonic acid.
The active substance of Atoris reduces the amount of cholesterol in the body and enhances the activity of low-density lipoprotein receptors in the liver and soft tissues, leading to their synthesis and elimination from blood plasma. The course of taking atorvastatin can reduce total cholesterol by almost 30-45%, low-density lipoproteins by 40-60% and triglycerides by 15-30%.
Also, the active component of Atoris is endowed with anti-atherosclerotic action, contributing to the inhibition of the replication of isoprenoids, which cause an increase in the thickness of the vascular wall. Atorvastatin has a positive effect on the structure of the cardiovascular system, reducing the level of apolipoproteins B and triglycerides, improving plasma viscosity and enhancing endothelium-dependent relaxation of veins, arteries and capillaries.
The active substance of a statin quickly goes through an absorption process, during which almost 80% is absorbed from the digestive tract. The maximum concentration of atorvastatin in blood plasma is observed 60-90 minutes after administration. In people of different age groups and gender, there are minor deviations in the indicators.
Also, important factors influence the duration of absorption of a substance:
    frequency of intake and composition of food;
    the patient has cirrhosis of the liver.
The agent has a low bioavailability, which is only 12%, while its inhibitory bioactivity to HMG-CoA reductase is more than 30%. The metabolic process of atorvastatin occurs in the liver with the use of cytochrome P450. The main substance of Atoris is converted into active metabolites, which are excreted from the body with bile and in small quantities with feces.

Indications for the start of admission

A statin drug is used for therapeutic and prophylactic purposes. It helps to eliminate the causes of development:
    primary and mixed hypercholesterolemia;
    familial type IV hyperlipoproteinemia;
    hereditary hyperlipidemia;
    familial hypercholesterolemia of the homozygous form.
Also, Atoris is widely used in the treatment of diseases of the cardiovascular system resulting from high blood plasma cholesterol. It is prescribed to patients with the following risk factors:
    ischemic heart disease;
    arterial hypertension;
    angina pectoris;
    stroke;
    diabetes mellitus;
    genetic predisposition;
    over 55 years of age;
    nicotine addiction.

Instructions for use

To achieve a positive result as quickly as possible, it is recommended to strictly follow the doctor's prescription. It is especially important to combine the course of treatment with an individually tailored lipid-lowering diet therapy.
Persons suffering from obesity should take 10 mg of atorvastatin per day, regardless of food intake. At the same time, the patient should receive moderate physical activity and healthy balanced food with a minimum amount of carbohydrates. In the absence of a positive result within four weeks of treatment, the dosage can be increased to 80 mg.
Since atorvastatin tablets are intended for a single daily use, it is worth setting a specific schedule in compliance with the exact time of administration. Drinking the medicine is worth a little water.

Contraindications for use

The medication of the statin group, which includes atorvastatin, is prohibited from taking:
    during lactation;
    during pregnancy;
    children and adolescents under 18;
    with individual intolerance to drug substances.
In addition, Atoris is not recommended for use by persons for whom there is a high risk of developing myotonia, liver cirrhosis, chronic hepatitis and liver failure. Also, an anti-cholesterol agent should not be taken in the presence of alcohol dependence and hypersensitivity to atorvastatin.

Side effect

In the presence of intolerance to atorvastatin, the patient may experience discomfort associated with the development of side effects. The active component of the drug in rare cases has a negative effect on various structures of internal secretion, accompanied by the following symptoms:
    on the part of the sense organs: decreased visual acuity, ringing in the ears, dryness of the mucous membrane of the eyes, deafness, impaired taste and parosmia;
    from the central nervous system: amnesia, headache, insomnia, dizziness, asthenic syndrome, mood instability and depression;
    from the cardiovascular system: chest pain, arrhythmia, migraine, vasculitis, hypertension and increased heart rate;
    from the respiratory system: rhinitis, shortness of breath, bronchitis, nosebleeds and asthma;
    from the gastrointestinal tract: dyspeptic syndrome, which is characterized by diarrhea, vomiting, pain in the abdominal region, heartburn, increased gas production, dry mouth and increased appetite;
    from the genitourinary system: vaginal bleeding, urolithiasis, cystitis, genital infections, impotence and ejaculation failure.
Also, the most common side effects are allergic reactions, which are characterized by skin rash, itching, redness and hives. In extremely rare cases, excessive sweating, seborrhea, eczema and ecchymosis were observed.
Individuals who are hypersensitive to atorvastatin may experience disturbances in the functioning of the musculoskeletal system: muscle cramps, back pain, myopathy, and joint swelling.
If you experience any of the above symptoms, you should immediately stop taking the statin and seek medical advice. In this case, it is possible to reduce the initial dose of Atoris or replace it with an analogue with another active substance.

Overdose

Exceeding the daily dosage of the medication is dangerous to human life. In case of an overdose, the patient is detoxified by the gastric lavage followed by the intake of sorbents. Then a complete examination is carried out, during which the capacity of the organs is determined and supportive therapy is prescribed.

Interaction with other medicinal products

The course of treatment for atherosclerosis and other diseases associated with an increase in blood cholesterol levels requires unquestioning adherence to the doctor's prescription. It is not recommended to use the following medications while taking Atoris:
    calcium channel blockers (diltiazem), which increase the plasma concentration of atorvastatin;
    antiarrhythmic and anti-tuberculosis drugs that reduce the effectiveness of a statin;
    antacids based on magnesium or aluminum, which help to reduce the saturation of the active substance of the lipid-lowering drug in the blood;
    antibiotics, fibrates, nicotinates and antifungal agents that worsen the patient's condition and complicate the course of the disease.
During the period of taking atorvastatin, natural grapefruit juice should be used with caution, which contributes to an increase in statin in the blood.

Special instructions

Treatment with a statin drug is recommended to be carried out taking precautions. Diabetics should take into account that cholesterol tablets contain milk sugar, so they should periodically monitor their blood glucose levels.
During the development of Atoris, no studies were conducted on the efficacy and safety of prescribing lipid-lowering drugs to children under the age of 18 years. That is why atorvastatin-based tablets are prohibited for patients of this age category.
Since there is a high risk of developing myalgia during the treatment period, the use of the medication should be carried out under the supervision of the attending physician. If muscle pain and weakness develop, statin use should be stopped immediately.
The active substance of the tablets often becomes the cause of the development of dizziness, therefore, during the course of therapy, it is necessary to abandon the control of a car and work, which requires increased attention and a good psychomotor reaction.

Storage conditions and periods

Atoris belongs to the medicinal list "B", which is characterized by storage at a temperature of + 15 to + 25 ° C and a relative humidity of no more than 60%. To preserve the useful properties of the medication, the optimal solution would be to keep it in a home first-aid kit, protected from heat and direct sunlight. It is recommended to store tablets in their original packaging for no more than 2 years from the date of manufacture.

Reviews

On the forums, the benefits and harms of the Atoris drug are discussed by patients and highly qualified doctors, who note that Atoris has a fast-acting effect, which makes it possible to achieve positive results in a short time and normalize the carbohydrate balance in the body.
However, there are negative reviews from people who had to experience the side effects of atorvastatin. Basically, patients note the development of mild allergic reactions and disorders of the digestive system. At the same time, participants talk about the elimination of symptoms of individual intolerance to the components of a statin after stopping taking the pills.
During the course of treatment, endocrinologists recommend in parallel to adhere to the correct therapeutic nutrition and exercise daily.

Terms of sell

You don't need a prescription to buy Atoris.