Zinnat tabs 250mg #10

Zinnat user manual

Reed more and buy Zinnat here

It has a wide range of actions. It has a bacteriostatic and bactericidal action due to a violation of the synthesis of the bacterial cell wall. The active ingredient of the drug - cefuroxime - acetylates membrane-bound transpeptidases, thus disrupting the cross-linking of peptidoglycans, which ensures the strength and rigidity of the cell wall.

Composition and release form

Clinico-pharmacological group: Cephalosporin II generation. Zinnat is available in the form of:
    Tablets 125 mg number 10;
    Tablets 250 mg number 10;
    Tablets 500 mg number 10;
    Granules for suspension preparation 125 mg / 5 ml in a vial of 100 ml № 1;
    Granules for the preparation of suspensions of 125 mg in sachet number 14;
    Granules for suspension 250 mg in sachet number 10.
One tablet contains: Cefuroxime (in the form of cefuroxime ascetyl) - 125 or 250 mg; Additional substances. Granules for suspension for oral use 100ml Cefuroxime (in the form of cefuroxime ascetyl) - 125mg / 5ml

What is Zinnat used for?

The indications for taking Zinnat antibiotic are:
    infection of the upper and lower respiratory organs (pharyngitis, sinusitis, bronchitis, pneumonia);
    infections of soft tissue and skin (pyoderma, furunculosis);
    urinary tract infection (urethritis, cystitis, pyelonephritis);
    gonorrhea;
    early stage Lyme disease treatment and prevention of the late stage of this disease.
Zinnat is an effective antibiotic for infectious-inflammatory diseases, if they are caused by microorganisms that are susceptible to the action of Zinnat. To predict the effectiveness of the application in a particular case, a drug sensitivity test is done.

pharmachologic effect

Cephalosporin antibiotic II generation broad-spectrum. It has a bactericidal effect by inhibiting the synthesis of the bacterial cell wall. Cefuroxime acetylates membrane-bound transpeptidases, thus disrupting the cross-linking of peptidoglycans necessary to ensure the strength and rigidity of the cell wall.
    Highly active against gram-negative bacteria: Escherichia coli, Haemophilus influenzae, Salmonella spp., Shigella spp., Proteus mirabilis, Neisseria gonorrhoeae, Enterobacter spp.
    Also active against gram-positive bacteria: Staphylococcus spp., Streptococcus spp.
Inactive against Pseudomonas spp., Most strains of Enterococcus spp., Many strains of Enterobacter cloacae, methicillin-resistant strains of Staphylococcus spp. and Listeria monocytogenes.

Instructions for use

According to the instructions for use, the course of treatment and the dose of Zinnat are selected by the attending physician individually in each case. The average dose of Zinnat:
    In the treatment of infections of the lower respiratory tract of mild and moderate severity: adults 250 mg 2 times a day; children 3-6 months 40-60mg 2 times a day; children 6 months - 2 years 60-120 mg 2 times a day; children 2-12 years old 125mg 2 times a day.
    In the treatment of severe infections of the lower respiratory tract or otitis media: adults 500 mg 2 times a day; children 3-6 months 60-90mg 2 times a day; Children 6 months - 2 years 90-180 mg 2 times a day; children 2-12 years old 180-250mg 2 times a day.
    In the treatment of infections of the urogenital system: adults, 125mg, 2 times a day.
    With pyelonephritis: adults 250 mg 2 times a day.
    In the treatment of uncomplicated gonorrhea: adults appoint 1 g once.
The standard course of therapy is 7 days (can vary from 5 to 10 days). For optimal absorption, Zinnat should be taken after meals.

Contraindications

Do not use the drug Zinnat in such cases:
    Individual hypersensitivity to cefuroxime and other cephalosporins.
    No experience with children younger than three months.
    Use with caution during pregnancy.
During lactation should stop breastfeeding at the time of use of the drug Zinnat.

Side effects

Frequent side effects noted when taking Zinnat:
    Headache, dizziness;
    Nausea, diarrhea, abdominal pain;
    Superinfection with Candida;
    Eosinophilia;
    Transient increase in the level of liver enzymes ACT, ALT, LDH.
In rare cases, possible:
    Vomiting;
    False positive Coombs reaction;
    Thrombocytopenia, leukopenia;
    Skin rash, pruritus, urticaria;
    Pseudomembranous colitis.
In isolated cases are noted:
    Jaundice (mostly cholestatic);
    Toxic epidermal necrolysis;
    Erythema multiforme;
    Hemolytic anemia;
    Drug fever;
    Anaphylaxis;
    Serum sickness;
    Hepatitis;
    Stevens-Johnson syndrome.
An overdose of cephalosporins can cause an increase in the excitability of the brain with the development of seizures. Treatment: conduct symptomatic therapy. Cefuroxime serum concentrations decrease with hemodialysis and peritoneal dialysis.

Admission precautions

Caution is prescribed to patients with suspected penicillin allergy. It should be borne in mind that the suspension is active for 10 days (stored at a temperature not exceeding 25 ° C); suspension prepared from sachets should be used immediately.

Terms and conditions of storage

The storage conditions of the drug are as follows:
    Tablets should be stored at a temperature not higher than 30 ° C. Shelf life - 3 years.
    Granules for the preparation of suspensions should be stored at a temperature not higher than 30 ° C. Shelf life - 2 years.
    The prepared suspension should be stored in a refrigerator at a temperature of 2-8 ° C for no more than 10 days.
Keep out of the reach of children.

Use in childhood

Contraindicated in children under 3 months (for suspension for oral administration); for tablets - children's age up to 3 years (for children from 3 months to 3 years, Zinnat should be used in the form of a suspension).

Reviews

Karina
We always use this antibiotic in the family on the advice of a very competent professor. We have no one had any side effects. By the way, if you compare the descriptions with other antibiotics, but it has the least side effects! Read about the rest and see for yourself! In some it is written: perhaps coma, death ...
Vika
Zinnat with otitis and bronchitis helped us a lot, a good preparation, everyone has side effects, but if we consider that the health of the child is more expensive, we must suffer, we had constipation after it, and otitis media and bronchitis cured.

Terms of sell

You don't need a prescription to buy Zinnat.