Unidox Solutab tabs 100mg #10

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Unidox Solutab instruction

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The drug also breaks the connection of some types of RNA with the ribosome membrane. Unidox Solutab is characterized by a significantly higher activity against cultures of microorganisms that are in a functional stage of growth and division, at the same time, the drug has practically no effect on microorganisms in the resting stage.

Composition and release form

Clinico-pharmacological group: an antibiotic of the tetracycline group.
    The active substance Unidox Solutab doxycycline monohydrate is supplemented with microcrystalline cellulose, lactose monohydrate, saccharin, colloidal silicon dioxide, anhydrous low-substituted hyprolose, magnesium stearate and hypromellose in the required amount.
The drug is produced in the form of tablets that dissolve in the oral cavity and do not have the need to swallow. The shape is biconvex, round. The color is a light yellow tone with a shade of gray. On one side there is a separation risk and a code letter 173 on the other side.

What is used Unidox Solutab?

The following diseases caused by bacteria are indications for the use of "Unidox Solutab":
Diseases of the genitourinary system:
    cystitis;
    endometritis;
    urethritis;
    gonorrhea;
    prostatitis caused by a bacterium;
    pyelonephritis;
    syphilis;
    chlamydial infections;
    urogenital mycoplasmosis.
Diseases of the digestive system and biliary tract:
    dysentery;
    cholecystitis;
    gastroenterocolitis;
    travelers diarrhea;
    cholera;
    yersiniosis;
    cholangitis.
Diseases of the respiratory system and ENT organs:
    acute bronchitis;
    tracheitis;
    pneumonia;
    pharyngitis;
    tonsillitis;
    otitis;
    sinusitis;
    lung abscess.
Other diseases:
    eye infections;
    sepsis;
    osteomyelitis;
    infections from insect bites or animals;
    chlamydia;
    whooping cough;
    typhoid fever;
    proctitis;
    Lyme disease;
    plague;
    malaria;
    ornithosis;
    bartonellosis;
    psittacosis;
    brucellosis;
    skin and soft tissue infections;
    peritonitis.


pharmachologic effect

Unidox Solutab contains the active ingredient - doxycycline - an antibiotic of the tetracycline group. Doxycycline has a bacteriostatic effect due to inhibition of synthesis and metabolic disorders of proteins contained in the cell membrane of microorganisms.
In addition, Unidox Solutab breaks the connection of certain types of RNA with the ribosome membrane. The drug is characterized by a significantly higher activity against cultures of microorganisms that are in a functional stage of growth and division, at the same time, the drug has almost no effect on microorganisms in the resting stage.

Instructions for use

The duration of the dose and the dosage of Unidox Solutab should be prescribed by the doctor, depending on the disease and its course. The tablets are swallowed whole or powdered and mixed with water. The drug is preferably taken with meals. Take the pill while sitting or standing, which reduces the likelihood of esophagitis and ulcers of the esophagus. The drug should not be taken immediately before bedtime.
    Adults and children over 8 years old with a body weight of more than 50 kg are prescribed 200 mg / day in 1 or 2 doses on the first day of treatment, and 100 mg / day in 1 dose on the following days of treatment. In the case of severe infections, 200 mg / day is prescribed for the entire period of treatment.
    For children aged 8-12 years old with a body weight of less than 50 kg, the average daily dose is 4 mg / kg on the first day, then 2 mg / kg / day (in 1-2 doses). In cases of severe infections, Unidox Solutab is prescribed at a dose of 4 mg / kg daily throughout the treatment.
Average dosage depending on the disease:
    For uncomplicated gonorrhea (with the exception of anorectal infections in men), adults are prescribed 100 mg 2 times / day until they are completely cured (an average of 7 days), or 600 mg are prescribed in one day, 300 mg in 2 doses (second dose 1 h after the first).
    For uncomplicated urogenital infections caused by Chlamydia trachomatis, cervicitis, non-gonococcal urethritis caused by Ureaplasma urealiticum, 100 mg are prescribed 2 times / day for 7 days.
    In primary syphilis, 100 mg is prescribed 2 times / day for 14 days, and in secondary syphilis, 100 mg 2 times / day for 28 days.
    For the prevention of travelers' diarrhea, 200 mg on the first day of a trip in 1 or 2 doses, then 100 mg 1 time per day during the entire stay in the region (no more than 3 weeks).
    For malaria prophylaxis, 100 mg is prescribed 1 time per day 1-2 days before the trip, then daily during the trip and for 4 weeks after returning; children over 8 years old - 2 mg / kg 1 time / day. The duration of prevention should not exceed 4 months.
    For acne, 100 mg / day is prescribed, the course of treatment is 6-12 weeks.
    In order to prevent infections during medical abortion, 100 mg is prescribed 1 hour before and 200 mg after the intervention.
    For the treatment of leptospirosis - 100 mg orally 2 times / day for 7 days; for the prevention of leptospirosis, 200 mg once a week during a stay in a deprived area and 200 mg at the end of the trip.
    For infections caused by Streptococcus pyogenes, the duration of treatment is at least 10 days.
The maximum daily doses for adults are up to 300 mg / day or up to 600 mg / day for 5 days with severe gonococcal infections. For children over 8 years old weighing more than 50 kg - up to 200 mg, for children 8-12 years old with a body weight less than 50 kg - 4 mg / kg daily during the entire treatment.


Contraindications

The drug Unidox Solutab can not be used in such cases:
    severe pathological changes in the liver and kidneys;
    pregnancy and lactation period;
    allergic reactions to tetracycline use;
    children under 12;
    porphyria.

Side effects of Unidox Solutab

When using the drug may develop the following adverse reactions:
    Manifestations of allergic reactions: urticaria, anaphylactic reactions, exacerbation of systemic lupus erythematosus, angioedema, pericarditis, erythema multiforme.
    Manifestations of the nervous system when using Unidox Solutab: increased intracranial pressure (headache, vomiting, swelling of the optic nerve), vestibular changes (dizziness), blurred vision, splitting in the eyes.
    Manifestations of the skin: exfoliative dermatitis, photosensitivity, maculopapular and erythematous rash.
    Manifestations of the circulatory system: hemolytic anemia, decreased prothrombin activity, thrombocytopenia, neutropenia, eosinophilia.
    Manifestations of the endocrine system: in patients who received doxycycline for a long time, reversible staining of the thyroid tissue in dark brown color can occur.
    Manifestations of the digestive tract: nausea, vomiting, diarrhea, dysphagia, anorexia, enterocolitis, esophagus ulcer, pseudomembranous colitis, esophagitis, darkening of the tongue, liver damage (with prolonged use or in patients with renal and hepatic insufficiency), cholestasis.
    Manifestations of the urinary system: an increase in residual urea nitrogen (as a result of anti-anabolic action).
    Manifestations of the musculoskeletal system: doxycycline disrupts the normal formation of teeth in children, irreversibly changing the shade of the teeth (enamel hypoplasia appears).
Other manifestations in the application of Unidox Solutab: causes candidiasis (stomatitis, proctitis, vaginitis) as the occurrence of superinfection.

Pregnancy and lactation

Unidox Solutab is not used during pregnancy unless the drug is the only means for treating or preventing particularly dangerous and severe infections (rocky mountain fever, inhalation effects of Bacillus anthracis, and others).
The active ingredient Unidox Solutab - Doxycycline, it penetrates into breast milk. Due to the adverse effects on the fetus, doxycycline, like other tetracyclines, is not used during breastfeeding. If the prescription of tetracyclines is necessary, breastfeeding should be discontinued.

Doxycycline or Unidox Solutab - which is better?

The main difference between the drugs is the fact that Unidox does not have such a strong effect on the stomach and does not cause side effects characteristic of doxycycline (gastric ulcer, gastritis).
The absorption of the active substance occurs in the intestine and almost 100% of the drug is absorbed by the body. The only advantage of doxycycline is its extremely low cost compared to the original.

Storage conditions

At a temperature from 15 to 25 ºС. Keep out of the reach of children! Shelf life: 5 years. Do not use beyond the expiration date printed on the package.

Reviews

Olga
They prescribed it for ureplazmoz, they said they should drink 10 days, but I read that you need to drink 2 days for ureplazmoz 2 tablets, I decided to drink a week, especially since the first days were very bad, nausea, pain in the intestines, it was dysbacteriosis. but I took these pills (not counting the first days) rather calmly, taking Hilak forte 40 drops before each meal + Unidox pill (if you drink it immediately before eating, then there is practically no nausea) and 2 capsules of Linex after eating; also at night a glass of acidophilus or kefir. if you will all follow this “diet” for 7 days, you will take this drug safely!

Terms of sell

You don't need a prescription to buy Unidox Solutab.