Furazolidone tabs 50mg #20

Furazolidone user manual

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Synthetic derivative of 5-nitrofurforol. The drug is effective in the treatment of inflammatory diseases caused by gram-negative aerobic bacteria. Gram-positive aerobic bacteria are less sensitive to it, as are fungi and protozoa.
Anaerobic pathogens are insensitive to furazolidone. The resistance of microorganisms develops slowly.
Disrupts the processes of cellular respiration of microorganisms, suppress the Krebs cycle, and also inhibit other biochemical processes of microorganisms, resulting in the destruction of their membrane or cytoplasmic membrane.
As a result of the drug's action, microorganisms emit less toxins, and therefore, it is possible to improve the patient’s general condition even before pronounced suppression of microflora growth.
Unlike many other antimicrobial agents, Furazolidone not only does not inhibit, but even activates the body's immune system (increases the complement titer and the ability of leukocytes to phagocytose microorganisms).
After ingestion, it is rapidly and almost completely absorbed in the intestine. Therapeutically significant blood concentrations are maintained for 5-6 hours after taking a single dose. Furazolidone penetrates liquor, where its concentration is the same as in the blood.

Indications for use

What is furazolidone used for? According to the instructions, the drug is prescribed in the following cases:
    Intestinal infections: paratyphoid fever, bacillary dysentery, foodborne toxicoinfection.
    Parasitic diseases: giardiasis.
    Urogenital tract infections: pyelitis, trichomonas urethritis, cystitis.
    In surgery: burns and infected wounds.

Instructions for use Furazolidone dosage

The drug is applied orally, after meals with plenty of water (except for local use in surgery). Treatment should not last more than 10 days.
Standard dosage, according to the instructions for use Furazolidone, depending on the evidence:
    With dysentery, paratyphoid and foodborne diseases - 100-150 mg / 4 times a day (but not more than 800 mg), for 5-10 days.
    When Giardiasis: adults - 100 mg \ 4 times a day, children - 10 mg / kg / day, distributing the daily dose in 3-4 doses.
    The highest single dose for adults - 200 mg, daily - 800 mg.
Additionally used for the treatment of burns and wound infections. In these cases, used topically in the form of wet-drying dressings, or irrigation with a solution of Furazolidone, in a ratio of 1: 25,000.

special instructions

During treatment, the drug should be temporarily excluded from the diet or sharply limit the products - cottage cheese, cream, butter, hard cheese, coffee, strong tea, herring.
In order to prevent the development of polyneuritis, the administration of Furazolidone tablets should be combined with the intake of B vitamins.

Side effects of Furazolidone

The instruction warns of the possibility of the development of the following side effects when prescribing furazolidone:
    loss of appetite, up to anorexia, nausea, vomiting;
    allergic reactions - skin rash, hyperemia and itching of the skin, angioedema.

Contraindications

It is contraindicated to appoint furazolidone in the following cases:
    severe chronic renal failure;
    pregnancy and breastfeeding;
    age of children under 3 years;
    increased individual sensitivity or intolerance to the components of the drug;
    cases of allergic reactions to drugs from the group of the nitrofuran series.
Assign with caution:
    chronic renal failure;
    liver disease, accompanied by dysfunction of the organ;
    diseases of the central nervous system.
The drug during pregnancy is contraindicated. It can be appointed only for vital needs, taking into account the expected and risk to the fetus. In animal studies, an adverse effect on the fetus was noted.

Overdose

Overdose symptoms are acute toxic hepatitis, hematotoxicity, neurotoxicity (polyneuritis).
The drug is canceled. Recommended intake of large amounts of fluid, symptomatic therapy, antihistamines and vitamins of group B.
There are no specific antidotes.

Reviews

Yuliya
Furazolidone was prescribed to the eldest son after giardiasis was discovered and naxojin did not help. There were no side effects, even though the son was allergic. To remove toxins in parallel, lactofiltrum was taken. Tablets inexpensive. But the main thing is that they work!
Svetlana
I was very pleased with these pills, they saved me from terribly unpleasant sensations. I took them from cystitis for a week, 1 tablet 3 times a day.
Dmitriy
Long-tried and familiar drug that works effectively, helps with problems
Galina
On the sea caught a cold and began Cystitis. Furazolidone he literally saved me. I am very grateful to this antibacterial drug. Nowadays, even surprisingly, such a cheap drug is not worse than expensive modern medicines.

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You don't need a prescription to buy Furazolidone.