Dioxidin solution infusions/injections 5mg/ml 5ml #10

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Dioxidin instruction

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Dioxidin is an antibacterial drug. As a chemical compound, it is a derivative of quinoxaline, which determines a wide spectrum of action against pathogenic and conditionally pathogenic microflora.
Anaerobic microorganisms, blue-green pus bacillus, Enterobacteriaceae, and enterococci are most sensitive to the drug.

Composition and release form

Under the simple and memorable trade name hides a complex organic substance called hydroxymethylquinoxalinedioxide. It is produced in two different dosages, and when buying Dioxidin for washing the nose with sinus this fact should be taken into account.
So, the Russian pharmaceutical companies produce Dioxidin solutions:
    solution in a concentration of 0.5%. This form of release is applied externally, intravenously and intracavitary, and is available in 10 and 20 ml ampoules.
    a solution in a concentration of 1%, which is intended for intracavitary and external use and packaged in glass ampoules containing 10 ml of the drug.
For rinsing the nasal cavity most often used the drug in a concentration of 0.1%.

What is Dioxidin used for?

The drug is used in surgery (neurosurgery), dentistry, urology, otolaryngology for various types and forms of purulent infection. Diseases for which Dioxidin helps:
    pustules on the skin;
    lung abscess, empyema, purulent pleurisy;
    secondary purulent meningitis, brain abscess;
    purulent mastitis, cystitis, peritonitis, sepsis;
    sore wounds with osteomyelitis;
    cellulitis, abscess on the skin, trophic ulcers, burns, postoperative, post-traumatic wounds (superficial and deep);
ENT-doctors prescribe instillation of the solution for rhinitis, sinusitis, otitis.

pharmachologic effect

Dioxidin is a broad-spectrum antibacterial drug.
When processing purulent wounds, damage to the integrity of the skin with a pronounced exudation (weeping surface of the wound, most often occurs with burns) Dioxidin solution accelerates wound cleansing, stimulates regeneration, and has a positive effect on the further course of the process.
    It is effective in infections caused by vulgar proteem (a type of microorganisms that can cause infectious diseases of the small intestine and stomach under certain conditions), a pyo-pus bacillus, dysentery bacillus and Klebsiella bacilli (Friedlander - the causative agents of pneumonia and local purulent processes), salmonella, staphylococcal , streptococci, pathogenic anaerobes (able to exist in the absence of oxygen by bacteria that cause human diseases), including the causative agents of gas gan Rena.
Well absorbed from the surface of the skin and mucous membranes when applied topically. Does not bind to blood proteins, is excreted unchanged through the kidneys with urine. Maximum concentration reaches 2 hours after administration. When i / in the method of administration does not have a broad therapeutic effect. Does not have the ability to accumulate (accumulation) in organs and tissues.


Instructions for use

Dioxidin solution according to the instructions for use prescribed in the hospital. Apply externally, intracavitary. Dioxidin 1% solution cannot be used for iv administration, due to the instability of the solution during storage at low temperatures.

Intracavitary introduction:

    The drug is introduced into the cavity usually 1 time / day. According to indications, it is possible to introduce a daily dose in two doses. With good portability and availability of indications, the drug can be administered daily for 3 weeks or more. If necessary, in 1-1.5 months they conduct repeated courses.
    Depending on its size, 10-50 ml of 1% Dioxidin solution / day is injected into the purulent cavity. The Dioxidin solution is injected into the cavity through a catheter, a drainage tube or a syringe.
    The maximum daily dose for the introduction into the cavity of 70 ml of 1% solution.

How to breed for a nose:

    Before you begin treatment, find out how to dilute Dioxidin to flush the nose. Learn to observe the right concentration, and no complications will arise. For an adult, medicine with a concentration of 0.5% is practically harmless. One-percent Dioxidin will have to be mixed with water in an equal ratio. If you have to treat a child, dilute 0.5% antibiotic with water in a ratio of 2: 1. To prepare a solution from a drug with a concentration of 1% per 1 part of the drug, use 3-4 parts of water.

External use:

    Apply 0.1-1% Dioxidin solutions. To obtain a 0.1-0.2% solution, the ampoule solutions of the drug are diluted to the desired concentration with sterile isotonic sodium chloride solution or water for injection.
    For the treatment of deep purulent wounds with osteomyelitis (wounds of the hand, foot), 0.5-1% solutions of the preparation are used in the form of baths or a special treatment of the wound with a solution of the preparation is carried out for 15-20 minutes (introduction of the solution into the wound for this period) 1% Dioxidin solution.
    For the treatment of superficial infected purulent wounds impose wipes moistened with 0.5-1% Dioxidin solution on the wound. Deep wounds after treatment, loosely tamped with tampons moistened with 1% Dioxidin solution, and in the presence of a drainage tube, from 0.5 to 100 ml of a 0.5% solution of the preparation is injected into the cavity.
    Dioxidin in the form of 0.1-0.5% solutions can be used to prevent infection after surgery. According to indications (patients with osteomyelitis) and with good tolerance, treatment can be carried out daily for 1.5-2 months.

How to do inhalation:

    To properly prepare the solution for inhalation, you need to monitor the proportion of the drug. If you are prescribed Dioxidin for sinus or sore throat, use a solution concentration of 0.25%. To do this, mix one part of a 0.5% drug with two parts of water. Dioxidin with a concentration of 1% is diluted in a double volume of liquid. For one inhalation, no more than 4 ml of solution is used.
When it comes to treating a child, in the process of preparing a solution for inhalation, use one and a half times more water (3: 1 for a drug with a concentration of 0.5% and 6: 1 for a drug with a concentration of 1%). The maximum volume of solution for one inhalation procedure is 3 ml. Calculate the concentration with utmost care, otherwise you can damage the mucous membranes.

Contraindications

The drug has contraindications:
    Hypersensitivity to the drug;
    Renal failure;
    Adrenal insufficiency.
It is strictly prohibited to women in the situation and nursing mothers, because it damages the fetus and causes gene mutations.


Side effects

With the introduction of Dioxidin into a vein or cavity, headache, chills, fever, dyspeptic symptoms (eating disorders), jerky mouse twitches are possible.
To prevent adverse reactions, it is recommended that anti-histamine preparations and calcium preparations be prescribed. If adverse reactions occur, reduce the dose, prescribe antihistamines, and, if necessary, stop taking Dioxidin.

Storage conditions

Keep out of reach of children, protected from light at a temperature of 18 ° to 25 ° C. Shelf life - 2 years.

Reviews

We picked up some reviews from people about Dioxidin:
Helena
    I usually use Dioxidin solution to treat my child’s prolonged rhinitis. I mix it in equal parts with aloe extract and drip twice a day. The tool is cheap and very effective. Does not overdry mucous and does not cause discomfort.
Anna
    Once in the early spring I had a congestion in the auricle. I tried to be treated by folk methods, but the disease only worsened. The otallarinologist prescribed Dioxidin drops. In this case, the doctor assured that the drug has absolutely no side effects. Having dripped into the ear a maximum dose of the drug, I felt a burning sensation. After that, read the instructions, and found a large number of side effects. For treatment, I reduced the dose and quickly cured the inflammation of the ear canal. I recommend this drug to everyone, but before using it carefully read the instructions.
Tanya
    Dioxidin is a very good medicine. I use it only for mixed drops, for the nose. With a cold that I cannot cure for more than a week or two, it is an indispensable tool! I was prescribed an ENT doctor, saying that even sinusitis is treated with mixed drops, patients do not have to pierce the sinuses. Here is the recipe: Dioxidin 1% - 5 ml, Mezaton - 2 ml, Dexamethasone - 2 ml = mix everything into 10 cubic meters. syringe, and 2 drops drop, 3 times a day. The nose is breathing, and the runny nose passes very quickly. The price is affordable, even very, and in all pharmacies you can find this drug.
Sasha
    I was prescribed Dioxidin in ampoules with furunculosis, which I placed on a gauze rolled up in several layers, which I dipped into the printed ampoule of the solution to the place where the furuncle had broken through. Doctors surgeons said that this medicine is an antibiotic and sucks pus well. In principle, he made his own work for his money and the wounds from the pus were cleaned quickly, faster than before, when they simply changed the dressings or Ihtyol ointment was applied.

Terms of sell

You don't need a prescription to buy Dioxidin.