Instruction for use of Anauran
You can buy Anauran on this page
Anauran is a drug belonging to the group of combined antibiotics. It is used strictly according to the doctor's prescription according to the instructions.
Form of release and composition of the drug
Anauran is available in the form of ear drops - a colorless transparent liquid packed in 25 ml darkened glass vials. The vials are equipped with a special dropper cap and packed in cardboard containers. The active components of the agent are a combination of polymyxin B sulfate, neomycin sulfate and lidocaine hydrochloride.
Additional substances per 100 ml of the product:
0.01 g of benzalkonium chloride;
44 ml of propylene glycol;
26.5 g glycerol;
purified water.
Anauran is made on the basis of an aminoglycoside, a local anesthetic and a cyclic polypeptide.
Pharmacological properties
The medication belongs to the pharmacological group of combined antibiotics that have a local anesthetic and antibacterial effect. Aminoglycoside (neomycin sulfate) has a broad spectrum of action.
Effective against gram-positive and gram-negative bacteria:
staphylococcus;
shigella of various shapes;
Proteus.
Anauran, according to the instructions for use, shows little activity against Streptococcus app. The polypeptide component of polymyxin B is used in pathologies associated with the action of gram-negative bacteria. Shows high activity against Escherichia coli, Shigella of various forms and varieties, Salmonella typhi (paratyphi), Pseudomonas aeruginosa.
Does not affect mycobacteria, proteas, gram-positive cocci, fungi varieties. Shows a weakly expressed analgesic effect.
Lidocaine is used as an anesthetic, helps to get rid of itching and pain associated with the reproduction of pathogenic microflora in the ear canal. The active ingredients promote blood flow to the damaged areas, thus providing a regenerating and anti-inflammatory effect and eliminating all manifestations.
Product properties:
stops and prevents further growth of pathogenic bacteria;
eliminates inflammatory reactions in the affected area;
helps to remove secretions, including purulent ones;
can be used as a prophylactic agent;
relieves puffiness of an allergic nature;
helps to strengthen local immunity.
It is prescribed and used strictly according to the indications of the attending otolaryngologist.
Pharmacodynamics and pharmacokinetics
Clinical studies of the pharmacokinetic and pharmacodynamic properties of the drug have not been conducted due to the topical application of the drug. In this case, systemic effects are not manifested.
Indications for use
The medication is intended to eliminate infectious and inflammatory processes in the ear cavity.
Indications:
the presence of chronic or acute external otitis media;
otitis media in the preperforative stage;
defeat by exudative otitis media of the middle ear in a chronic form;
purulent complications arising from surgical operations - fenestration, mastoidectomy, antrotomy.
The drug is used strictly according to the indications of a specialist and under his constant supervision in order to avoid the development of complications. Before use, you must make sure that there are no allergic reactions to the components of the product.
Contraindications
Anauran, the instructions for the use of which permits the use of the agent in almost all cases of ear lesions by infectious and inflammatory processes, has some restrictions on use.
Contraindications:
children's age up to 1 year;
hypersensitivity or intolerance to one of the components of the drug;
the presence of allergic reactions in the area of the auricle - itching, peeling, hyperemia;
the period of pregnancy and breastfeeding.
It is forbidden to use the product while taking certain medications.
At what age can the drug be used
Drops are allowed to be used by children who have reached 12 months. For newborns, the medication is strictly contraindicated.
Instructions for use, drug dosage
The dosage of Anauran depends on the patient's age and the form of the pathological process:
Adults are shown 4-5 drops from 2 to 4 times a day. In children under 12 years of age, the recommended dosage is 2-3 drops 3-4 times a day.
The dosage for children from 1 to 3 years old is selected individually by the attending specialist.
The duration of therapy is 3-7 days. In this case, the course should not be more than 7 days due to the high risks of developing resistance of pathogenic microorganisms to the components of the drug. The drug is applied locally. The instillation is carried out using a special pipette or dispenser, which is equipped with most of the vials.
Method of application, instruction:
In case of a one-sided inflammatory process, instillation must be performed in both ears.
Before using the product, tilt your head to the side for better distribution of the product.
At the end of the procedure, it is recommended to stay with your head tilted for 3-5 minutes.
With the simultaneous appointment of several drugs of various forms, it is necessary to consult with a specialist about the rules for using drops.
With otitis media
Anauran is used in combination with oral antibiotics due to damage to the ear canals and the body by a bacterial infection. In addition, any suitable anesthetic may be prescribed.
Anauran is indicated for otitis media of various degrees of severity and forms of the disease. Effective in the treatment of otitis media, with purulent discharge, in acute and chronic form. The drug has an anti-inflammatory effect, fights a viral infection that provoked the development of the disease.
Buried in the ear canal from 3 to 5 drops daily no more than 4 times a day. After instillation, it is recommended to remain in the supine position for a few minutes for better distribution and absorption of the product. It is allowed to use a cotton swab or turunda.
With perforation of the tympanic membrane
Anauran, the instructions for use of which indicates the possibility of using the drug in inflammatory reactions, also helps to relieve puffiness and relieve pain. To provide a stronger therapeutic effect, the use of the agent should be combined with the intake of oral antibiotics.
During treatment, it is necessary to protect the ears from water ingress. It is prohibited in childhood and during the period of bearing a child due to the high risks of developing a toxic effect.
With eustachitis
Due to the fact that the drops have a pronounced bactericidal effect aimed at suppressing most gram-positive and gram-negative microorganisms, the agent is often prescribed for eustachitis.
Anauran effectively fights against pathogenic microflora, is highly active against hemophilus influenzae and whooping cough sticks. In this connection, it is often prescribed in the treatment of acute respiratory bacterial infections. Treatment regimen for adults: 4-5 drops of the drug in each ear 2-4 times a day. Children are shown no more than 2-3 drops 3-4 times a day.
After applying the drops, it is recommended to spend a few minutes with your head tilted to prevent the agent from flowing out of the ear canal. It is allowed to use a gauze pad or turunda. The duration of therapy should not exceed 7 days. Do not use during pregnancy and childhood.
Side effects
Anauran, the instructions for the use of which claims about minimal side effects, are usually well tolerated by patients. Adverse reactions may occasionally occur. In most cases, local allergic reactions occur in the form of redness, itching and burning in the area of the inlet.
These side effects go away on their own within a few days or after the drug is discontinued. Systemic reactions are completely absent due to the use of low doses of the drug.
With prolonged use, due to the high degree of absorption of neomycin, ototoxicity and nephrotoxicity may occur - toxic kidney damage. In such cases, it is necessary to immediately contact the attending specialist to prescribe symptomatic therapy and determine further actions aimed at eliminating the negative consequences.
Overdose
No cases of drug overdose have been identified. If the dose indicated by the attending specialist is exceeded, it is recommended to contact a medical institution for examination.
Special instructions
With the development of severe and neglected conditions, it is recommended to supplement therapy with other systemic antibiotics. Long-term drug treatment can provoke sensitization or the development of superinfection with microorganisms that have developed resistance to the antibiotic.
Abuse of Anauran can lead to the development of neurosensory disorders and cause permanent hearing loss. It is necessary to take the drug while carrying a child only as a last resort and under the strict supervision of a specialist.
There are no data on the interaction of Anauran and ethanol. However, it is recommended to refrain from drinking alcohol for the entire period of treatment. The medication does not affect the ability to drive vehicles or carry out work related to increased concentration.
Drug interactions
Drops Anauran can cause the development of resistance while taking drugs from the aminoglycoside group.
Anauran is completely incompatible with streptomycin, monomincin, gentamicin, amikacin.
When used together, the drug and netilmicin can lead to an ototoxic effect.
Terms of sell
You can buy Anauran without a prescription.