Tavegyl injections 1mg/ml 2ml #5

Tavegyl injections instruction

You can buy Tavegyl injections on this page

The composition of Tavegyl in solution

Active substance of Tavegyl

2 ml of solution contain: 2.68 mg of clemastine hydrofumarate, equivalent to 2 mg of clemastine.
2 ml of an ericinous Grammy: 2 mg clemastinge of balamala 2.68 mg of clemastine hydrofumarate.

Excipients in Tavegyl injections

2 ml of solution contain: sorbitol, ethanol 96%, propylene glycol, sodium citrate, water for injection.
2 ml of an ericinous Grammy: sorbitol, ethanol 96%, propylene glycol, sodium citrates, injection of arnalғan su.

Indications for use of Tavegyl solution

    prevention or treatment of allergic and pseudo-allergic reactions, including with the introduction of contrast agents, blood transfusion, diagnostic use of histamine
    angioedema, anaphylactic shock or anaphylactoid reactions, as an additional means
    Allergies Allahs Allergies Allerny Alu Zhemdeu, Sons ңshіnde contrasts Zattar Engіzu, қan құyu, Histamine Diagnostics қoldanu Kezіnde
    angioneuroticus, anaphylactic shock, nemesis, anaphylactoididitis, reactionary, osimsha dәrі retіnde

Contraindications Tavegyl in solution

    hypersensitivity to clemastine and other antihistamines of similar chemical structure or any of the excipients
    rare hereditary fructose intolerance, due to the content of sorbitol in the drug
    porphyria
    pregnancy and lactation
    children up to 1 year

Carefully

    in patients with stenosing gastric and duodenal ulcers, pyloroduodenal obstruction, with bladder neck obstruction, prostatic hypertrophy, accompanied by urinary retention, with increased intraocular pressure and angle-angle glaucoma.

Side Effects of Tavegyl Solution

Often (from ≥ 1/100 to <1/10)
    increased fatigue
    sedation
Sometimes (from ≥ 1/1000 to <1/100)
    dizziness
    dyspnea
    hypersensitivity reactions
Rarely (from ≥ 1/10000 to <1/1000)
    headache
    irritability
    nausea, epigastric pain, dry mouth
    urticaria, skin rash
Very rare (<1/10000)
    constipation
    tachycardia
    anaphylactic shock.

Special instructions for Tavegyl injections

Intra-arterial administration of the drug is not allowed!
Intravenous management should be carried out slowly (for more than 2–3 minutes).
Special care should be taken when using Tavegyl injections in patients with stenosing gastric ulcer, pyloroduodenal obstruction, bladder neck obstruction, and prostatic hypertrophy, with urinary retention, increased intraocular pressure and angle-closure glaucoma.
The preparation contains ethanol, therefore it is not recommended for people suffering from alcoholism.
It is also necessary to take into account the presence of ethanol in the appointment of children and patients belonging to a high-risk group (liver disease, epilepsy).
Features of the influence of the drug on the ability to drive a vehicle or any other potentially dangerous mechanisms.
Tavegyl injections, has a slight or moderate sedative effect, so it is recommended to refrain from driving a vehicle and working with any other potentially dangerous machinery.

Dosage and method of use

    Adults: the average dose is 2 mg / 2 ml, that is, the contents of 1 ampoule. The drug is administered intravenously or intramuscularly in the morning and evening.
    For prophylactic purposes, the drug is administered intravenously slowly at a dose of 2 ml immediately before the possible occurrence of an anaphylactic reaction or reaction in response to the use of histamine. The solution of the drug can be further diluted with isotonic sodium chloride solution or 5% glucose solution in a ratio of 1: 5.
    Children: 0.025 mg / kg per day intramuscularly, dividing the pre-dosage into two injections.

Drug interactions

Tavegyl injections enhances the action of drugs that depress the central nervous system (hypnotic drugs, sedatives, anxiolytics, tricyclic antidepressants, opioid analgesics), M-holinoblokatorov, as well as alcohol. Not compatible with the simultaneous use of monoamine oxidase inhibitors. Enhances the effect of warfarin (anticoagulant).

Tavegyl overdose in solution

Symptoms: An overdose of antihistamines can lead to both oppressive and stimulating effects on the central nervous system, which results in depression of consciousness, increased irritability, hallucinations and convulsions. Phenomena of anticholinergic action may also develop: dry mouth, fixed pupil dilation, flushing to the upper half of the body, gastrointestinal disturbances (nausea, epigastric pain, vomiting) and possibly tachycardia.
Treatment: Symptomatic therapy.

Pharmacokinetics

Communication with plasma proteins is 95%. Clemastine undergoes significant metabolism in the liver. Metabolites are mainly (45-65%) excreted through the kidneys with urine; unchanged active substance is found in urine only in trace amounts. During lactation, a small amount of clemastin can pass into breast milk.

Pharmacodynamics

Tavegyl injections are an H1 receptor antagonist. It refers to antihistamines from the group of benzohydryl ethers, reduces capillary permeability, has antiallergic and antipruritic effect, characterized by a rapid onset and a significant duration of action, reaching 12 hours.

Packaging and release form

On 2 ml of a preparation in ampoules of colorless glass of a hydrolytic class I. On 5 ampoules in the plastic pallet together with the instruction for medical application in the state and Russian languages ​​place in a pack from a cardboard.

Terms of sell

You don't need a prescription to buy Tavegyl injections.