Momat Rhino Advance spray 140mcg + 50mcg/dose 150doses

Momat Rhino Advance instruction

You can buy Momat Rhino Advance here

The manual contains up-to-date information on the composition of the Momat Rhino Advance spray, indications and dosing, side effects and contraindications, as well as other details for the correct use of the drug.

Form, composition, packaging

The drug in the form of a dosed nasal spray is a white suspension.
The complex of active substances consists of azelastine hydrochloride and mometasone furoate. It is supplemented with microcrystalline cellulose, purified water, sodium carmellose, sodium citrate, dextrose, citric acid monohydrate, polysorbate 80, neotame, benzalkonium chloride, edetate disodium.
The drug is sold in HDPE bottles one by one in a carton box. Each bottle is equipped with an adapter for the nose and a device for dispensing.

Term and storage conditions

Spray nasal afraid of freezing. It can be stored for two years in blackout at 15-25 degrees indoors. Children to the drug is not allowed.

Pharmacology

The drug of combined composition is used in the practice of ENT for the purpose of anti-inflammatory and antiallergic effect. Used locally. Its pharmacological properties are due to the action of the active substances contained in the medicine.
Azelastine, which provides a long lasting effect against an allergic reaction. It is a histamine H1 receptor blocker capable of exerting membrane stabilizing, antiallergic, and antihistamine action. Its functions include reducing exudation and capillary permeability. Azelastine does not allow the release of substances with biological activity from the mast cell, which leads to the development of bronchospasm and other types of allergic (early / late) response and inflammation.
Mometasone - GCS synthetic local, which contributes to the provision of antihistamine action with a clear anti-inflammatory effect. The range of its capabilities includes: inhibiting the release of inflammatory mediators, reducing the production of inflammatory exudate by preventing accumulations of marginal neutrophils, reducing granulation and infiltration processes. The substance of an active nature helps to reduce inflammation, affecting the reaction of allergies "late" type and inhibition of reactions like "immediate."

Pharmacokinetics

The bioavailability of the drug after using intranasal no more than 40 percent. The maximum concentration in the blood plasma reaches a maximum of three hours. It binds with blood proteins almost completely (by 90%).
The metabolism process is carried out in the liver with the participation of the cytochrome P450 system. With biotransformation, desmethylazelin is formed as an active metabolite.
Excretion through the kidneys. The half-life of metabolites: inactive - twenty hours, active (dezmetilazelastina) at least 45 hours.
Mometasone fuorate has a bioavailability of a systemic nature of not more than one percent. The suspension form of the drug, getting into the digestive tract after application intranasally, is practically not absorbed and undergoes primary metabolism rather actively before excretion by means of bile or urine.

Indications for use Momat Rhino Advance

The drug is recommended for use for the treatment of adult age group of patients with rhinitis allergic type: seasonal, year-round and others.

Contraindications for Momat Rhino Advance

Medicinal spray should not be prescribed to those patients who
    in recent times, the operation was carried out in the nasal cavity or the nose was injured, damaging the mucous membrane until the injuries go to the healing stage;
    are under the age of eighteen;
    suffer from hypersensitivity to the components of the drug.
Careful use of the drug requires in the presence of infections in the respiratory tract:
    tuberculosis;
    fungal;
    bacterial;
    systemic viral;
    herpetic (with damage to the eyes).

Momat Rhino Advance: instructions for use

The use of the drug is carried out intranasally using nozzles for dosing.
It is prescribed in one dose twice a day in the morning and evening hours in each nasal passage. Reception duration - 14 days.

Instructions for use of the dispenser bottle

    Remove the protective cap.
    The first use of the spray should be preceded by “calibration” by pressing the dispensing device at least ten times. If the vial has not been used for more than a week, it is enough to double-click to “calibrate” again until splashes from the dispenser appear.
    From the sides of the adapter, place the middle and index finger, and place a large one at the bottom of the bottle and inhale with a nose to press.
    Nasal adapter do not pierce.
    Do not allow the adapter to be directed towards the eyes when spraying.
    Before you spray the spray, clean the nostrils.
    Holding the bottle in a vertical position, insert the tip of the adapter into the nasal passage with another, holding it with your free hand. Make a sharp single click.
    Exhale through the mouth.
    Do the same for the other nasal passage.
    Wipe the adapter with a cloth and replace the cap for protection.

Cleaning the nasal adapter

    Cap off.
    Remove the adapter by gently pulling it upwards.
    Do not use foreign objects to wash the adapter in cold running water.
    Dry in the air.
    Rinse and dry the cap.
    Return the nasal adapter to its place, making sure to place the vial stem in the center of the adapter.
    Carry out calibration presses until stable fine dispersion is released.
    Replace the cap for protection.

The use of different categories of patients

During pregnancy

During pregnancy, the use of the drug Momat Rhino Advance is not recommended, because the drug has not been studied for this category of patients.
When used in animals, one of the active ingredients of the drug azelastine hydrochloride caused toxicity in the fetus during fetal development.

For kids

Children spray is not appointed until adulthood.

Side effects

When using the medicinal spray Momat Rhino Advance, the following side effects were observed:
    Nervous system: Patients complained of frequent headaches, less frequently on the development of vertigo. A feeling of an unpleasant taste in the mouth was also noted, which is explained by the incorrect use of the spray, when the patient tilts the head too far back when injected.
    Digestive system: In rare cases, nausea, pharyngeal irritation (mucous membrane) was recorded.
    Respiratory system: Quite often, the treatment was accompanied by bleeding from the nose and uncomfortable sensations in the area of ​​use of the spray. There was ulceration of the nasal mucosa, as well as the development of infections of the upper respiratory tract, sinusitis, pharyngitis. Often patients suffer from repeated sneezing.
    Immunity: In rare cases, development of urticaria, hypersensitivity reactions or anaphylactoid reactions have been noted.
    Skin integument / subcutaneous tissue: Occasionally, itchy skin rash has been reported.
    Miscellaneous: Rare manifestations of drowsiness, fatigue or weakness that may occur due to the disease itself.
Long-term use, especially in excessive doses, can lead to the development of systemic side effects. No exception cataract / glaucoma.

Overdose with Momat Rhino Advance

Cases of overdose spray when it is used correctly are not fixed. However, when the patient uses the drug with impaired and the contents of the bottle gets inside, the negative effects of azelastine, one of the active ingredients of the drug, can develop. This is fraught for the patient with the development of drowsiness, hypotension, tachycardia and confusion. In this situation, treatment is carried out based on the symptoms.

Drug interactions

Applied strictly intranasally spray Momat Rhino Advance does not enter into drug interactions with other medicines, which would entail clinical significance.

Additional instructions

If there is a need for prolonged therapy with this spray, the patient should undergo periodic examination to identify changes in the nasal mucosa, as well as possible perforation of the nasal septum, infectious fungal diseases in the pharynx / nose area or other systemic side effects. Which in turn will require the abolition of drug therapy with a spray and further special treatment of the identified pathological conditions.
At the beginning of use in the treatment of the spray Momat Rhino Advance, after discontinuing the use of systemic corticosteroids, the patient may complain of symptoms characteristic of the latter being canceled in the form of joint / muscle pain, depression and increased fatigue, allergic reactions (eczema, conjunctivitis) are not excluded, which at acceptance of the GKS of the system action could be disguised. However, discontinuing treatment with a spray against the background of these complaints is not worth it, since this therapy is one of the most effective options, and such symptoms will soon disappear by themselves.
If you allow overestimation of dosages during treatment with a spray nasal Momat Rhino Advance in a patient, in addition to the effects of systemic side effects, there may be signs of suppression of the adrenal function. In this situation, you must gradually cancel the spray.
It is necessary to warn the patient that, during the period of treatment with GCS, he should not come into contact with people suffering from infections (measles / chickenpox), because when receiving glucocorticosteroids, the patient has the potential risk of lowering immune reactivity.
When taking the medication, a manifestation of a bacterial infection of a pronounced nature (fever, toothache or swelling and pain on either side of the face) is not excluded, in this situation it is necessary to urgently visit a doctor.
Nasal corticosteroids, as well as those intended for inhalation, can develop cataracts or glaucoma in those patients who suffer from impaired vision. Therefore, such patients need particularly careful observation when they are prescribed Momat Rhino Advance spray therapy.
Sometimes during treatment with a spray, the work related to the control of machinery and vehicles should be postponed, because those consequences that cause the disease that is treated with this medicine in the form of increased fatigue and weakness, dizziness can reduce the patient's ability to work.

Momat Rhino Advance: reviews

Reviews of this drug come regularly. Mostly speak positively about the spray as an effective means of allergies. Of course, there are also those who are not completely satisfied with the medicine due to the development of side effects or its high cost, but there are few of them.
Polina

I was recommended to take this medicine by an allergist because of the presence of an antihistamine substance in his active complex. It should be noted that the appointment of two injections per day was enough for me one so it is effective. Sensation of congestion and itching in the nasal cavity pass almost instantly after the use of the drug. This spray helps me a lot when aggravating seasonal allergies. I recommend it to all my friends who also suffer from allergic rhinitis. There is no need to use the medicine for a long time, therefore I did not notice any side effects. The cost of the spray suits me perfectly, as I have enough bottle for the season. I advise you to pay attention.
Vadim

Spray Momat Rhino Advance began to apply for the purpose of the ENT. The fact is that the last year I can’t get rid of the cold. The doctor said that the medicine is characterized by the accumulation effect and perhaps the therapeutic action of the spray will not manifest itself immediately. Indeed, after a week of admission, I began to notice that the runny nose retreated and was almost no longer disturbing. But I decided to carry out a medical course to the end, using this medicine in combination with other medicines for a cold. The result of the treatment is very good. The taste and smell of the drug is completely absent. Which facilitates its reception. The bottle is also very convenient for injection with a dispenser. The cost of the drug seemed high, but it would pay more for such effective assistance. Recommend.
Irina

Due to the development of one of the viral infections, it took several months to suffer from the lack of smell. What the doctors did not prescribe for me for this period even before the operation almost got it. However, one of the doctors suggested not to hurry with surgical intervention and try a complex of drugs, among which the main emphasis was offered on treatment with the spray Momat Rhino Advance. Indeed, the treatment helped, now I breathe well with my nose and I can distinguish odors. The cost of the spray is quite acceptable, if we take into account its analogues. Therefore, the choice in favor of this drug is obvious. Using the drug is easy because of the side effects a little nauseated, but it's the little things. The medicine helped me a lot, so I can recommend it safely.
Victoria

Being an allergic with experience, always looking for a remedy for allergies with the onset of spring. Although my relatives as soon as they can, they try to protect me from the effects of flowering and the awakening of nature still suffer very much from the congestion itching in my nose and from the fact that my eyes are constantly watering. It should be noted that medicines today often have such a cost that they do not know how to approach them. Recently, the doctor advised to try Momat Rhino Advance in the form of a spray. I immediately noted that it is much cheaper than the drug that I used recently and bought for testing. Now only this spray: it helps effectively, it is not so expensive, I have no side effects. I recommend to try those who need such help.

Terms of sell

You don't need a prescription to buy Momat Rhino Advance.