Hexicon supp 16mg #10

Instruction for Hexicon

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Hexicon is a broad-spectrum antiseptic.

Release form and composition

Dosage forms:
    Vaginal suppositories: torpedo-shaped, white with a yellow tinge or white, marbling of the surface is allowed (5 pcs. In a blister, 2 packs in a cardboard box or 1 pc. In a blister, 1 pack in a cardboard box);
The active substance of Hexicon is chlorhexidine bigluconate:
    1 suppository - 16 mg;
Excipients:
    Suppositories: polyethylene oxide 1500 and polyethylene oxide 400;

Pharmacodynamics

Chlorhexidine is an antiseptic for external and local intravaginal use. It is active against some viruses, protozoa, gram-positive and gram-negative bacteria, which include Herpes simplex type 2, Treponema pallidum, Bacteroides fragilis, Chlamydia spp., Gardnerella vaginalis, Ureaplasma spp., Trichomonas vaginalis, Neisseria. Some strains of Proteus spp. Exhibit a slight sensitivity to the drug. and Pseudomonas spp., fungi, bacterial spores, strains of microorganisms showing acid-fast properties are also resistant to it. Chlorhexidine does not affect the functional activity of lactobacilli and retains its pharmacological properties in the presence of purulent contents and blood (its effect on the body is somewhat weakened).

Pharmacokinetics

With intravaginal administration, the systemic absorption of chlorhexidine is considered insignificant. When applied topically and locally, the drug is practically not absorbed. In case of accidental swallowing of a dose of 300 mg, the maximum concentration of chlorhexidine is determined after 30 minutes and is equal to 0.206 μg / L. Its excretion is carried out mainly with feces (90% of the dose used), less than 1% of the active substance is excreted in the urine.

Indications for use

According to the instructions, Hexicon in the form of tablets and suppositories is used in the following cases:
    Prevention of sexually transmitted pathologies, including syphilis, chlamydia, gonorrhea, trichomoniasis, genital herpes, ureaplasmosis;
    Treatment of vaginal dysbiosis, vaginitis of various etiologies, including Trichomonas, mixed, nonspecific;
    Prevention of infectious and inflammatory complications in gynecology and obstetrics: before intrauterine examinations, childbirth, abortion or surgical treatment of gynecological diseases, as well as before and after the installation of an intrauterine device or diathermocoagulation of the cervix.

Contraindications

It is recommended to use the drug with caution for the treatment of patients in childhood.
The use of Hexicon is contraindicated in case of hypersensitivity to the components of the drug.

Instructions for the use of Hexicon: method and dosage

    Suppositories: intravaginally, 1 pc is prescribed for therapy. 2 times a day. The course of treatment is 7-10 days. For the prevention of sexually transmitted infections, 1 suppository is administered once during the first 2 hours after unprotected intercourse;

Side effects

Sometimes the use of chlorhexidine causes the development of allergic reactions, itching, which disappear after the cancellation of the drug.

Overdose

Since the systemic absorption of Hexicon is rather low, the risk of drug overdose is minimized. Cases of adverse reactions when using high doses of Hexicon have not been described at the moment.

Special instructions

Hexicon is effective in preventing sexually transmitted infections if it is used within two hours of intercourse.
Organic substances and the presence of blood impurities do not affect the activity of chlorhexidine.
Avoid contact of the drug with the auditory nerve and meninges.
In case of contact with the mucous membranes of the eyes, they must be quickly rinsed with water.
The bactericidal property of the solution increases with an increase in its temperature.

Application during pregnancy and lactation

It is allowed to use Hexicon during pregnancy and lactation, but only after consulting a specialist and carefully balancing the possible benefits of treatment for the patient and potential risks to the fetus and child.

Drug interactions

Soap inactivates the action of the drug, therefore, before external procedures, it is recommended to thoroughly rinse the affected areas with running water.
Hexicon is not compatible with detergents: sodium lauryl sulfate, sodium carboxymethyl cellulose, saponins.
Simultaneous treatment with iodine-containing drugs is not recommended.
Allowed simultaneous use with preparations of the cationic group - benzalkonium chloride, cetrimonium bromide.
Ethanol increases the efficiency of the solution.

Terms and conditions of storage

Store out of the reach of children, protected from light at a temperature not exceeding 25 ° C.
Shelf life - 2 years;

Reviews

Reviews of the Hexicon - both positive and negative - are quite common. Patients mention the advantages of the drug, which include hypoallergenicity and a mild effect on the body, the effectiveness and speed of the drug, ease of use, the possibility of prophylactic use and the safety of using Hexicon during pregnancy and lactation. Negative opinions about the intravaginal forms of the drug are associated with the fact that after administration, the suppositories quickly dissolve and begin to flow, which causes certain inconveniences, as well as with adverse reactions manifested in the form of bloody discharge, burning and itching.
Experts and patients consider Hexicon the safest and most effective remedy for the treatment of pregnant women, which in some cases has practically no analogues. Expectant mothers use vaginal suppositories and tablets at different stages of pregnancy for therapeutic purposes, as well as for prophylaxis shortly before childbirth. For some, the remedy helped immediately, while others had to undergo a second course of treatment.
There are reports that Hexicon did not help some patients and even provoked allergic reactions. Some reviews contain information about the appearance of a pinkish discharge from the vagina, which requires immediate consultation with a doctor. There is also a risk of confusing the flow of "melted" suppositories out of the vagina with the discharge of cork or water. To avoid discomfort, it is often recommended to use panty liners or panty liners.

Terms of sell

A prescription is not required to buy Hexicon.