Gynofort cream 20mg/gr 5gr

Gynofort user manual

You can buy Gynofort here

Gynofort is an imidazole derivative, antifungal agent with fungicidal action, active against fungi of the genus Microsporum, Trichophyton, Epidermophyton and Candida.

Release form and composition

Dosage form - vaginal cream: homogeneous, without visible stratification and foreign particles, from white to white with a gray tint (5 g each in polypropylene applicators, 1 applicator in a polystyrene box, 1 box in a laminated bag, 1 bag in a cardboard box).
Active ingredient: butoconazole nitrate, in 1 g of cream - 20 mg.
Additional components: polyglyceryl-3-oleate, glycerol monostearate, wax, mineral oil, colloidal silicon dioxide, propyl parahydroxybenzoate, methyl parahydroxybenzoate, propylene glycol, disodium edetate, sorbitol, water.

Pharmacodynamics and pharmacokinetics

Gynofort refers to antimycotic drugs that are used in gynecology for the local treatment of vaginal infections caused by fungi.
Butoconazole - the active substance of the drug - is an imidazole derivative and has a fungicidal effect. It is fatal to fungal strains of the genus Epidermophyton (epidermophytosis), Candida (thrush), Microsporum (ringworm), Trichophyton (trichophytosis). The drug blocks the transformation of lanosterol into ergosterol in the cell membrane of the fungus and increases the permeability of the membrane, promoting the lysis (decay) of fungal cells.
The bioadhesiveness of the cream is quite high. With a single intravaginal use of the drug, butoconazole is determined on the vaginal mucosa for 4-5 days.
Systemic absorption of butoconazole with the introduction of the drug into the vagina is 1.7% of the recommended dose. The maximum plasma concentration of this substance is 2–18.6 ng / ml and is reached 13 hours after the drug is administered.
In the body, butoconazole is extensively metabolized and undergoes partial excretion through the kidneys and intestines.

Indications for use

Gynofort is used to treat vaginal candidiasis caused by Candida albicans.

Contraindications

The use of the drug is contraindicated in girls under 18 years of age, pregnant and breastfeeding women, as well as all patients with hypersensitivity to its components.

Instructions for the use of Gynofort: method and dosage

Gynofort is intended for single intravaginal use.
The contents of 1 applicator are inserted deep into the vagina.
The time of day the drug is used does not matter.
Rules for using the disposable applicator:
    Remove foil from packaging;
    Remove the applicator;
    Without removing the cap, take the applicator firmly with one hand, and with the other pull the ring to the limit in order to pull the piston out of it;
    Gently insert the applicator deep into the vagina;
    Slowly pressing the plunger, squeeze out the cream;
    Remove empty applicator and discard.

Side effects

    Local reactions: soreness, itching, burning, swelling of the vaginal wall;
    Others: cramps and / or pain in the lower abdomen.

Overdose

Cases of overdose with topical application of the drug are currently not known. In case of accidental swallowing (oral ingestion) of the contents of the applicator, you should cleanse the digestive tract (rinse the stomach and intestines) and undergo a course of symptomatic therapy.

Special instructions

The applicator is intended for single use.
Do not heat the applicator and use if the cap is removed.
The preparation contains parabens that can cause allergic reactions.
If, after the end of treatment, clinical signs of infection persist, it is necessary to conduct a second microbiological study to identify the pathogen and confirm the diagnosis.
In case of painful sensations or irritation of the vaginal mucosa, treatment should be discontinued.
In case of accidental ingestion of Gynofort cream into the gastrointestinal tract, it is necessary to wash the stomach and, if necessary, carry out symptomatic treatment.
The drug does not have a negative effect on attention and speed of reactions.

Application in children

It is prohibited to use Gynofort in pediatric practice.

Pregnancy and lactation

Although, according to the official instructions, Gynofort is contraindicated in pregnant and lactating mothers, in some cases it is prescribed to patients with diagnosed vaginal candidiasis. Previously, the specialist must carefully weigh the ratio of the benefits to the mother and the likely risks to the fetus or child and warn the patient about the possible consequences of such therapy.

Drug interactions

The preparation contains mineral oil, which can damage rubber and latex products (including intravaginal diaphragms and condoms), therefore, it is not recommended to use these contraceptives within 72 hours after the injection of Gynofort cream.
There is no information on interactions with other medicinal products.

Terms and conditions of storage

Store at a temperature of 15-25 ° C out of the reach of children.
Shelf life is 3 years.

Reviews about Gynofort

In most cases, reviews about Gynofort are favorable. It effectively fights vaginal candidiasis, including in pregnant women. The drug is characterized by high efficiency of treatment, rare and minor manifestations of side effects and ease of use due to a single use. Some patients speak negatively about the drug, noting its high cost.

Terms of sell

You can buy Gynofort without a prescription from a doctor.