Baralgin M injections 500mg/ml 5ml #5

Baralgin M injections user manual

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Indications

Arthralgia, rheumatism, chorea, pain: headache, dental, menstrual, neuralgia, ischialgia, myalgia, with colic (renal, hepatic, intestinal), lung infarction, myocardial infarction, dissecting aortic aneurysm, arterial thrombosis, inflammatory processes, inflammatory processes. , lumbago, myocarditis), injuries, burns, decompression sickness, shingles, tumors, orchitis, pancreatitis, peritonitis, esophageal perforation, pneumothorax, posttransfusion complications, priapism; febrile syndrome in acute infectious, purulent, and urological diseases (prostatitis), insect bites (including mosquitoes, bees, gadflies).

Contraindications for Baralgin M injections

Hypersensitivity, inhibition of blood formation (agranulocytosis, cytostatic or infectious neutropenia), severe dysfunction of the liver or kidneys, prostaglandin bronchial asthma, hereditary hemolytic anemia associated with deficiency of glucose-6-phosphate dehydrogenase, pregnancy, breast-feeding.

Composition

Active ingredient: Metamizole sodium.

Release form

1. Tablets 500 mg; 2. Solution for intravenous and intramuscular administration of 25%; 3. Solution Baralgin M for intravenous and intramuscular administration of 50%; 4. Suppositories rectal 100 mg; 5. Rectal suppositories 250 mg.

Mode of application

Intramuscularly, intravenously, rectally. Intrusion or intravenous (with severe pain) - 1–2 ml of 50% or 25% solution 2-3 times / day, maximum daily dose of 2 g; children are given 0.1–0.5 ml. Inside, after a meal, or rectally, at 250–500 mg 2-3 times / day, the maximum single dose is 1 g, daily dose — 3 g. The usual dose for children of 2-3 years is 50–100 mg, 4–5 years old 100–200 mg, 6–7 years old — 200 mg, 8–14 years old — 250–300 mg 2–3 times / day.

Interactions

The effect is enhanced by barbiturates, codeine, caffeine, H2-antihistamines, propranolol (slows down inactivation). Sarkolizin and tiamazol increase the likelihood of developing leukopenia. Sedatives and tranquilizers enhance the analgesic effect of metamizole sodium. Tricyclic antidepressants, oral contraceptives, allopurinol violate the metabolism and increase toxicity. Simultaneous use with other antipyretic analgesics, NSAIDs can lead to mutual enhancement of toxic effects, with chlorpromazine or other phenothiazine derivatives - to the development of severe hyperthermia. Myelotoxic drugs increase the hematotoxicity of metamizole sodium. Phenylbutazone and other inducers of liver microsomal enzymes weaken the effect.
Metamizole sodium, displacing from the connection with blood proteins, increases the activity of oral hypoglycemic drugs, indirect anticoagulants, HA, indomethacin. Enhances the sedative effect of alcohol. Reduces the concentration of cyclosporine in plasma. Radiocontrast agents, colloidal blood substitutes and penicillin should not be used during treatment with metamizole sodium. Due to the high likelihood of pharmaceutical incompatibility can not be mixed with other drugs in the same syringe.

Side effects of Baralgin M injections

Granulocytopenia, agranulocytosis, thrombocytopenia, hemorrhage, hypotension, interstitial nephritis, allergic reactions (including Stevens-Johnson's syndrome, Lyell's syndrome, bronchospasm, anaphylactic shock).

special instructions

When treating children under 5 years of age and patients receiving cytotoxic drugs, Metamizole sodium should be taken only under medical supervision. Intolerance is very rare, but the threat of anaphylactic shock after intravenous drug administration is relatively higher than after ingestion of Baralgin M injections. Patients with atopic bronchial asthma and pollinosis have an increased risk of allergic reactions. Agranulocytosis may develop during the administration of metamizole sodium, and therefore the detection of an unmotivated rise in temperature, chills, sore throat, difficulty swallowing, stomatitis, as well as the development of vaginitis or proctitis, requires immediate withdrawal of Baralgin M injections. With prolonged use, it is necessary to control the picture of peripheral blood. Use for removal of acute abdominal pains (before finding out the reason) is inadmissible. For i / m injection, you must use a long needle. Possible staining of urine in red due to the release of the metabolite (does not matter).

Terms of sell

You don't need a prescription to buy Baralgin M injections.