Amigrenin tabs 100mg #6

Amigrenin user manual

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Migraine is a neurological disease characterized by severe headaches, often accompanied by nausea and vomiting, a disorder of the gastrointestinal tract, visual impairment, numbness of the hands, tongue. Pain can be localized in the region of the eyes or crown, often only one half of the head is covered with pain. The duration of migraine attacks - from several hours to 3 days.
In this article we will consider why doctors prescribe Amigrenin, including instructions for use, analogues and prices for this drug in pharmacies. Real reviews of people who have already taken advantage of Amigrenin can be read in the comments.

Composition and release form

Amigrenin - tablets, film coated. In blister packs of 2 tablets.
    1 tablet contains the active ingredient - sumatriptan succinate in the amount of 70 or 140 mg (sumatriptan 50 or 100 mg).
    Additional components: microcrystalline cellulose, sodium carboxymethyl starch, lactose, magnesium stearate, potato starch.
Clinico-pharmacological group: 5 HT1 receptor agonist. Drug with anti-migraine activity.

What helps Amigrenin?

When is it recommended to start taking Amigrenin (analogues)? Reviews of doctors say that if you have a seizure of severe pain in the temple or frontal lobes once a month or more often, which is accompanied by additional signs (nausea, dizziness, tinnitus), then you should always keep the drug in your first-aid kit .
It will not cure, but it will greatly facilitate your life. So, the drug was created specifically to stop acute migraine attacks with or without aura, and to eliminate the pain syndrome.

pharmachologic effect

According to the instructions, Amigrenin is an anti-migrainous agent, a specific selective serotonin 5HT1B-1D agonist.
    The use of the drug contributes to the selective narrowing of blood vessels in the carotid artery system, reducing the processes of neurogenic inflammation. In this case, the drug does not have a pronounced effect on the cerebral blood flow. It is also experimentally established that sumatriptan slows down the activity of the trigeminal nerve.
Together, the above effects contribute to pain during a migraine attack. The therapeutic effect of taking the drug develops in about half an hour.

Instructions for use

According to the instructions for use, Amigrenin is not intended for use for the purpose of prevention.
Adults are prescribed in a single dose of 50 mg, in some cases, 100 mg. The maximum daily dose is 300 mg.
If the symptoms of migraine do not disappear and do not decrease after taking the first dose of Amigrenin, then the drug should not be prescribed again to relieve an ongoing attack. If the symptoms have decreased or disappeared, and then resumed, you can take a second dose over the next 24 hours. The interval between doses of the drug should be at least 2 hours.

Contraindications

Contraindications for taking Amigrenin, according to the instructions, are the following states:
    Age up to 18 years;
    Age over 65;
    Angina pectoris;
    Coronary heart disease;
    Stroke;
    Liver failure;
    Ophthalmoplegic, basilar or hemiplegic forms of migraine;
    Pregnancy and lactation;
    Transient cerebrovascular accident (in history);
    Uncontrolled increase in blood pressure;
    Individual intolerance to any of the components of the drug;
    Occlusive peripheral artery disease.
Amigrenin is used with caution in controlled arterial hypertension, epilepsy, while taking it with MAO inhibitors and for 14 days after the end of their intake.

Side effects

The drug causes an increase and decrease in blood pressure. Also Amigrenin can cause the following side effects:
    With intranasal use - itching, burning sensation in the nasal cavity, nosebleeds.
    Various allergic reactions - rash, itching, anaphylactic shock.
    Nausea, vomiting, rarely - increased transaminase activity of the liver, abdominal discomfort, ischemic colitis, dysphagia.
    Diplopia, nystagmus, decreased visual acuity, partial loss of vision can be extremely rare.
    Dizziness, drowsiness, weakness, rarely - epileptic seizures (if epilepsy is present in the patient's history).
    Disorders of the cardiovascular system - tachycardia, bradycardia, palpitations, severe cardiac arrhythmias, myocardial infarction, transient ECG changes, extremely rare - Raynaud's syndrome.
With adequate intake of the drug, not exceeding the permissible daily dose, almost no adverse reactions are almost never observed. Excess doses of the drug above the level of the average therapeutic dosage, develop symptoms of side effects. When they occur, you must stop taking the pills and seek medical help.

special instructions

Particular care should be taken when prescribing the drug to epileptics, with controlled arterial hypertension or to people with low seizure activity. In order to avoid spasm of the coronary arteries in patients with diseases of the cardiovascular system, the first dose should be made under the supervision of a physician.
The interaction of Amigrenin with lithium salts can lead to the development of serotonin syndrome, with moclobemide - to increase the bioavailability of the latter. The use of the drug with the herb St. John's wort can cause increased serotonergic action and the development of side effects.

Reviews about Amigrenin

There are many good reviews about Amigrenin on the Internet forums. The drug quickly helps and relieves agonizing migraine headache.
Sometimes there are side effects, but patients still continue to take the drug, because, in their opinion, this is the only way to avoid seizures.
Daria
Before these pills, with a headache, they could eat up to 10 different Pentalgin and other medicines, but alas. Nothing helped. According to my painful descriptions, my daughter found an explanation for such a headache on the Internet and offered to try a medicine of the Sumatriptan group.
Amigrenin really helps me literally within 20 minutes. And no pain. Feel like a workable person! More help pills Sumatriptan-Teva. It is Teva-manufacturer. They are much cheaper, but also 2 pieces per pack. I wish you all HEALTH !!!

Storage conditions and shelf life

The medicine must be stored in a dark and dry place. Shelf life is 2 years.

Terms of sell

You can buy Amigrenin without a prescription.