Angidak spray 0.255mg/dose 176doses

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Angidak instruction

You can buy Angidak here

The drug Angidak - NSAIDs for topical use in ENT practice and dentistry.
Benzidamine is a non-steroidal anti-inflammatory drug, belongs to the group of indazoles. It has an anti-inflammatory and local anesthetic effect, has an antiseptic effect against a wide range of microorganisms, and restores microcirculation. The mechanism of action of the drug is associated with stabilization of cell membranes and inhibition of prostaglandin synthesis.
Benzidamine has an antibacterial and specific antimicrobial effect due to the rapid penetration of microorganisms through the membranes, followed by damage to cellular structures, impaired metabolic processes and cell lysosomes.
It has an antifungal effect against Candida albicans. It causes structural modifications of the cell wall of fungi and their metabolic chains, thus preventing their reproduction, which was the basis for the use of benzidamine in inflammatory processes in the oral cavity, including infectious etiology.

Pharmacokinetics

When applied topically, the drug is well absorbed through the mucous membranes and penetrates into the inflamed tissues; it is found in the blood plasma in an amount insufficient to produce systemic effects.
Excretion of the drug occurs mainly by the kidneys, in the form of inactive metabolites or conjugation products.

Indications for use

Angidak spray is used in the symptomatic treatment of pain syndrome of inflammatory diseases of the oral cavity and ENT organs (of various etiologies):
- gingivitis, glossitis, periodontal disease, stomatitis (including after radiation and chemotherapy);
- pharyngitis, laryngitis, tonsillitis;
- candidiasis of the oral mucosa (as part of combination therapy);
- calculous inflammation of the salivary glands;
- after surgical interventions and injuries (tonsillectomy, jaw fractures);
- after treatment and tooth extraction.
In infectious and inflammatory diseases requiring systemic treatment, it is necessary to use the drug as part of combination therapy.


Mode of application

Angidak spray is applied topically after meals.
One dose (one injection) corresponds to 0.255 mg of benzidamine.
Adults (including elderly patients) and children over 12 years of age - 4-8 injections 2-6 times a day.
Children from 6 to 12 years old - 4 injections 2-6 times a day.
Children from 3 to 6 years old - 1 injection for every 4 kg of body weight, but not more than 4 injections (maximum single dose) 2-6 times a day.

A course of treatment

The duration of treatment is 7 days; if after 7 days of treatment improvement does not occur, it is necessary to consult a doctor.

Directions for use

1. Turn the cannula (white tube) to the “vertical to vial” position.
2. Insert the cannula into the mouth and direct it to the sore spots in the mouth and throat.
3. Press the dosing pump on the top of the vial as many times as the doses prescribed. One click corresponds to one dose. Hold your breath while injecting.
Caution: Before first use, press the spray gun several times into the air.
Do not exceed recommended dose. Before use, consult your doctor.

Side effects

Classification of the incidence of side effects according to the World Health Organization (WHO):
In each group, unwanted effects are presented in decreasing order of severity.
Local reactions: rarely - dry mouth, burning in the mouth; frequency unknown - numbness in the mouth.
Allergic reactions: infrequently - photosensitivity; rarely - hypersensitivity reactions, skin rash, skin itching; very rarely - angioedema, laryngospasm; frequency unknown - anaphylactic reactions.
If any of the side effects specified in the instructions are aggravated, or any other side effects not listed in the instructions are noted, you should immediately inform your doctor.


Contraindications

Contraindications to the use of Angidak spray are: hypersensitivity to benzidamine or other components of the drug; children under 3 years old.
With caution: hypersensitivity to acetylsalicylic acid or other non-steroidal anti-inflammatory drugs, bronchial asthma (including history).

Pregnancy

Angidak should not be used during pregnancy and during breastfeeding.

Interaction with other drugs

No studies have been conducted on the interaction of Angidak with other drugs.

Overdose

No cases of drug overdose have been reported at this time.
Symptoms: when using the drug Angidak in accordance with the instructions for use, an overdose is unlikely. If the drug is accidentally swallowed, the following symptoms are possible: vomiting, abdominal cramps, anxiety, fear, hallucinations, cramps, ataxia, fever, tachycardia, respiratory depression.
Treatment: symptomatic; empty the stomach by inducing vomiting, or rinse the stomach using a stomach tube (under the supervision of a doctor); provide medical supervision, supportive care, and adequate hydration. The antidote is not known.

Storage conditions

Angidak spray should be stored at a temperature not exceeding 25 ° C. Keep out of the reach of children.

Release form

Angidak - topical spray dosed 0.255 mg / dose.
88 doses (15 ml) or 176 doses (30 ml) in vials of high density polyethylene with a pump and with a pressure device with a folding cannula.
On 1 bottle together with the application instruction in a pack from a cardboard.

Composition

1 dose of Angidak spray contains: benzidamine hydrochloride 0.255 mg.
Excipients: ethanol 95% - 13.89 mg, glycerol (glycerin) - 8.52 mg, methyl parahydroxybenzoate - 0.17 mg, menthol flavoring - 0.051 mg, sodium saccharinate - 0.041 mg, sodium bicarbonate - 0.019 mg, polysorbate 20 - 0.009 mg, sodium hydroxide solution 1 M or a solution of hydrochloric acid 0.5 M - up to pH 5.0-7.0, water d / i - up to 170 μl.

Additionally

When using the drug Angidak, the development of hypersensitivity reactions is possible. In this case, it is recommended to discontinue treatment and consult a doctor to prescribe appropriate therapy.
In a limited number of patients, the presence of ulcers in the throat and oral cavity may indicate the presence of a more serious pathology. If symptoms persist for more than 3 days, consult a doctor.
The use of the drug is not recommended in patients with hypersensitivity to acetylsalicylic acid or other non-steroidal anti-inflammatory drugs. The drug should be used with caution in patients with a history of asthma due to the possibility of developing bronchospasm in patients with the drug. The drug contains parahydroxybenzoates, which can cause allergic reactions. The drug contains 13.2 mg of ethanol in a single dose (single injection). Ethanol content in a single dose:
- for adults (including elderly patients) and children over 12 years old - 52.8 - 105.6 mg;
- for children from 6 to 12 years old - 52.8 mg;
- for children from 3 to 6 years old - 13.2 mg of ethanol for every 4 kg of body weight, but not more than 52.8 mg (maximum single dose).

Terms of sell

You can buy Angidak without a prescription.