Cyanocobalamin injections 500mcg 1ml #10

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Cyanocobalamin instruction

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Cyanocobalamin (from lat. Cyanocobalamin) is a vitamin of group B (B12). It has a pronounced red color of bright shades and a water-soluble character. If the body is in insufficient quantities, significant problems can arise, which you will learn about below.

What is cyanocobalamin necessary for?

Considering what this vitamin is, it is worth noting the important functions of a biological nature that it performs:
    integral to the synthesis of blood elements and hemoglobin, in case of a deficiency anemia actively develops, due to the slow production of new red blood cells;
    protects the body by combating foreign bodies, produces white blood cells;
    has a calming effect on the nervous system of the human body;
    maintains the reproductive function of men.
The main component of the active substance of cyanocobalamin is cobamine. After introduction into the human body, B12 greatly increases the synthesis of methionine, increases immune defense.
It has a positive effect on the respiratory system. There is the ability to increase blood pressure, respectively, for various specific diseases, such as hypotension, its purpose is a vital necessity. It is a prophylactic against insomnia, allows you to effectively and smoothly adapt to all changes in the regime, for example, with a sharp change in time zones.

What could be the consequences of cyanocobalamin deficiency

Among the main causes of vitamin B12 deficiency it is customary to single out the following factors: poor or insufficiently balanced human diet; the effect of postoperative symptoms on food absorption; problems associated with the work of the digestive tract.
Consequences of deficiency:
    significant problems in the normal functioning of the nervous system, the most common symptoms are depression, sleep loss, lack of sensitivity, excessive irritability, tinnitus, hallucinogenic visions, severe drowsiness;
    memory impairment, increased likelihood of developing sclerosis and depression;
    problems associated with the normal functioning of the digestive tract, including constipation, bloating and flatulence, and sometimes up to peptic ulcers;
    an increase in the size of the liver;
    intensive formation of anemia.
    It is important to understand that even qualified specialists can hardly detect a deficiency of vitamin B12 in the human body, which for many years will consume all available reserves in order to offset its deficiency. A great risk is any diets that are used by people without the consent of doctors.
Vegetarians and vegans are at increased risk. This is due primarily to the fact that the food ration of these people, in connection with their moral and ethical beliefs, does not contain animal proteins. In addition, women who bear a child, elderly people, patients with AIDS and even those who suffer from constant diarrhea are most in need of the active use of cyanocobalamin.


Indications for the use of cyanocobalamin

When a person develops a health problem, vitamin deficiency is one of the reasons this happens. What vitamin is deficient in the body can only be determined by a qualified doctor.
A deficiency of cyanocobalamin is characterized by diseases such as chronic anemia. It is often prescribed in the complex treatment of anemia of other varieties, for example, which were caused by an overdose of drugs or poisoning.
Various central nervous system problems. Among the most common diseases are:
    sclerosis;
    myelosis;
    Down's disease;
    paralysis in children;
    neuralgia.
Skin problems, for example:
    atopic dermatitis;
    liver problems
    hepatitis B, A .;
    jaundice;
    radiation sickness.
Sometimes, some doctors call it as a prophylactic in the presence of pathologies in the gastrointestinal tract associated with the absorption of vitamin B12.

Application, methods and doses

When prescribing vitamin cyanocobalamin, the instructions for use note the presence of several options: subcutaneously, orally, intramuscularly, intravenously and intralumbally.
The vaccine is administered subcutaneously, with Addison-Birmer anemia, of posthemorrhagic and iron deficiency types. The dose, respectively, is equal to a value of 100-200 μg daily and from 30 to 100 μg 3 times a week. For some other types of anemia, B12 is used in combination with folic acid. Aplastic anemia, primarily in pediatric patients, involves the introduction of a drug of 100 mcg until the onset of a clear improvement.
In professional sports, characterized by an increased consumption of nutrients in the body, injections are most often prescribed intramuscularly or intravenously. In this case, the dosage size is about 1 mcg daily for one or two weeks.
If there are problems and diseases associated with the human central nervous system, the dose size is from 200 to 500 mcg every other day, for several weeks.
With hepatitis and liver diseases, 30-50 mcg is prescribed daily, or 100 mcg every other day. The duration of the course is from 25 to 40 days.
With Down's disease and cerebral palsy in young children, 15-30 mcg every other day is prescribed.
In radiation sickness, 60-100 mcg is administered every month during the month.
In the presence of sclerosis or myelosis, administration can be made intralumbally on a daily basis. The course lasts one month with a constantly increasing dose, from 15-30 micrograms at the beginning to 200-250 micrograms at the end of the course.


Drug action

Absorption occurs in the intestine, then with the help of special transport proteins is delivered to the desired parts of the body. It is stored in the liver, from which with the help of bile it is sent to the intestine for re-absorption. Directly excreted by the kidneys.
Vitamin B12 has a strong biological activity, increases the rate of tissue repair, eliminates hematopoiesis, normalizes the functioning of the liver and central nervous system, increases blood coagulation, slightly reduces cholesterol.

Special instructions and contraindications

During the period of taking the drug, doctors monitor the number of red blood cells, reticulocytes. Remission can be obtained with a strong increase in the number of red blood cells to values ​​of approximately 4 million / μl. When it is achieved, reticulocytes normalize, and poikilocytosis disappears. Surveillance is performed approximately every six months.
Contraindications of vitamin B12 can occur in individuals who have a congenital predisposition to blood clots in the human body, as well as with angina pectoris. As well as for many other drugs, you need to take it carefully and do not exceed the dose in the presence of pregnancy in women or in the process of breastfeeding. A categorical ban on complex use with drugs that increase blood coagulation.
Storage requires a dry, dark place.

Side effects of Cyanocobalamin

When taking this vitamin, various side effects may occur. Among the most common symptoms are the following:
    allergic reactions;
    excessive excitement of the mental type;
    tachycardia;
    uncontrolled diarrhea;
    pain and dizziness.
In the case when B12 is used in too large quantities, the development of hypercoagulation is possible. In addition, in rare cases, there are pulmonary edema, heart failure, and in some situations completely anaphylactic shock. In each case, treatment is carried out to eliminate the symptoms that have appeared.

Interaction with other drugs

Cyanocobalamin in ampoules, it cannot be combined with solutions of some other vitamins, for example, B1 and B6. This limitation is due to the fact that cobamine, which is contained in vitamin B12, completely destroys all other vitamins.
From a pharmaceutical point of view, this vitamin is completely incompatible with ascorbic acid. Also, you can not combine it with salts of various heavy metals or riboflavin. Some other medicines may simply decrease your effectiveness, such as colchicine.
When used with oral contraceptives, a sharp decrease in effectiveness is potentially possible due to a decrease in the volume of cyanocobalamin in plasma.
Using vitamin B12 along with anticonvulsants, its absorption from the digestive tract is reduced.
Medicines containing potassium, aminosalicylic acid and ranitidine reduce the level of absorption of vitamin from the gastrointestinal tract.
The parenteral use of chloramphenicol is characterized by a decrease in the effect of hematopoietic cyanocobalamin in all types of anemia.

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