Aspirin Cardio tabs 100mg #56

Instruction for Aspirin Cardio

Reed more and buy Aspirin Cardio on this page

Dosage form and composition

Aspirin Cardio is produced in the form of biconvex tablets containing 100 mg or 300 mg of active ingredients, which include:
    hydroxypropyl dichloromethane phosphate;
    acetylsalicylic acid;
    sodium dodecyl sulfate;
    emulsifier E553b;
    food additive E460;
    ethyl alcohol citric acid;
    oxyethylated sorbitans;
    copolymer of isobutenic acid and ethacrylate.
Tablets are packed in blisters of 10-12 pieces. The white-green box contains 20, 28 or 56 tablets and instructions for the use of NSAIDs.

Pharmacotherapeutic properties

The therapeutic effect of the antithrombotic drug is due to the properties of acetylsalicylic acid. Antiplatelet activity is explained by the ability to inhibit the production of enzymes involved in the production of prostaglandins. A decrease in the concentration of inflammatory hormones leads to a decrease in the severity of pain syndrome, hyperthermia and inflammatory reactions.
Aspirin Cardio inhibits the aggregation of platelets (platelets), as a result of which their adhesive properties are reduced. This effect occurs as a result of inhibition of the production of type A2 eicosanoids in platelets. If you start taking pills with an exacerbation of symptoms of angina pectoris or thromboembolism, the antiplatelet effect will appear within 5-7 days.
The analgesic properties of the drug are not pronounced, which is associated with a decrease in the susceptibility of neurons to irritating effects. Due to the regression of inflammatory reactions, a decrease in body temperature is observed. Therefore, Aspirin is often used in the symptomatic treatment of respiratory diseases.

Indications for use

The antiplatelet agent is used in the treatment of all types of diseases, accompanied by excessive thrombus formation, inflammation and hyperthermia. Indications for the appointment of Aspirin Cardio are:
    smoking;
    thromboembolism;
    vascular embolism after surgery;
    prevention of ischemic heart disease;
    hypertonic disease;
    large vein thrombosis;
    impaired blood microcirculation;
    pulmonary infarction;
    angina pectoris;
    prevention of myocardial infarction;
    ischemic attacks;
    diabetes;
    hyperlipoproteinemia;
    elderly age;
    prevention of cerebral infarction.
It is recommended to start taking the medication at the first signs of peripheral venous thrombophlebitis. In complex therapy, NSAIDs are used to reduce the severity of venous insufficiency and normalize rheological blood parameters.

Dosing regimen

Aspirin Cardio is taken 60 minutes before meals, without chewing, with 200 ml of drinking (still) water. The daily dose of an antiplatelet agent depends on the characteristics of the course of pathologies and the likelihood of thrombus formation:
    prevention of myocardial necrosis - 200-300 mg per day for 1 month;
    prevention of thromboembolism after surgery - 300 mg every other day;
    rehabilitation after myocardial infarction - 100-300 mg per day for 2-3 weeks;
    prevention of angina pectoris - 100-300 mg per day;
    embolism of arteries in the lungs - 100-200 mg per day for 15-20 days;
    diabetes mellitus and hyperlipidemia - 100 mg per day.
To prevent thrombosis in the development of multifactorial cardiovascular pathologies, 200 mg of the drug is prescribed per day. After achieving the desired therapeutic effect, it is advisable to start supportive therapy, which involves taking no more than 100 mg of Aspirin per day.

Special instructions

Acetylsalicylic acid may cause side effects in patients with nephropathy and renal failure. In case of impaired glomerular filtration and organic lesions of the kidneys, it is necessary to reduce the daily dose of the anti-thrombotic agent to 100 mg. The same applies to patients with congestive heart failure and bleeding tendencies.
Antiplatelet tablets, when ingested into the gastrointestinal tract, are metabolized using liver enzymes, followed by the formation of several active metabolites: salicyluric acid, phenyl salicylate, etc. In case of damage to the parenchyma, it is recommended to reduce the therapeutic dose of the drug to 100-200 mg per day, which is associated with the risk of increasing the plasma concentration of these substances.
It is undesirable to take Aspirin Cardio to persons with recurrent peptic ulcer disease. Medicinal metabolites irritate the gastrointestinal mucosa, which can lead to exacerbation of symptoms of the disease and internal bleeding.
The instructions do not recommend prescribing Aspirin Cardio to children who have not reached the age of 16. Salicylic acid can cause serious adverse reactions, including Reye's syndrome, indomitable vomiting, inflammation of the stomach lining, etc.

Alcohol compatibility

The ethyl alcohol contained in alcohol potentiates the antiplatelet activity of the drug, which is fraught with the occurrence of internal bleeding. In this regard, Aspirin Cardio is not recommended to be combined with the intake of alcoholic beverages and medicines.

Gestation and lactation

Inhibition of the biosynthesis of prostaglandins negatively affects the embryonic development of the fetus. The available clinical data indicate a high probability of miscarriage with the use of tablets during gestation. According to the results of animal tests, the tablets have pronounced reproductive toxicity.
Taking an antithrombotic drug in the third trimester of pregnancy can be accompanied by the development of cardiopulmonary toxicity and renal dysfunction. In this regard, Aspirin Cardio is not prescribed to patients during gestation and lactation.

Interaction with medicines

In the case of combined use, the antithrombotic drug potentiates the activity of the following medicines:
    indirect anticoagulants - increase the likelihood of internal bleeding;
    valproic acid - increases the toxic activity of salicylic acid;
    digoxin - increases the drug load on the liver due to impaired renal excretion of metabolites;
    selective serotonin reuptake inhibitors - increase the risk of bleeding from the upper digestive tract;
    methotrexate - increases the hematological toxicity of NSAIDs.
Antiplatelet tablets should be taken with caution when using diuretics. NSAIDs reduce the biosynthesis of prostaglandins in the kidneys, as a result of which the rate of glomerular filtration decreases.

Overdose cases

Overdose symptoms are manifested in the case of the use of toxic doses of a medication - more than 100 mg per 1 kg of body weight for two days. The most pronounced signs of salicylate intoxication of the body include:
    increased sweating;
    dizziness;
    confusion of consciousness;
    noise in ears;
    metabolic acidosis;
    severe headaches;
    hyperventilation;
    tachypnea;
    hearing loss;
    vomiting.
To reduce the severity of signs of poisoning, gastric lavage is performed, as well as forced diuresis. Then the patient is prescribed medications to restore water and electrolyte balance.

Side effects

As with other NSAIDs, Aspirin Cardio can cause short-term damage to vital organs. Common adverse reactions include:
    cramping abdominal pain;
    flatulence;
    headaches;
    stool disorders;
    thrombocytopenic purpura;
    eosinophilia;
    hemorrhoidal syndrome;
    bronchospasm;
    swelling of the throat;
    anaphylactic shock.
Less often, patients are diagnosed with decreased renal function, peptic ulcers and pancreatitis. In case of hypersensitivity to NSAIDs, symptoms of dermatosis and urticaria may appear.

Contraindications

It is strongly not recommended to take pills in the presence of the following diseases:
    peptic ulcer;
    severe heart failure;
    hemorrhagic diathesis;
    cirrhosis of the liver;
    renal failure;
    peptic ulcers.
The drug is not prescribed for hypersensitivity to salicylic acid and methyl salicylates.

Terms of sell

You can buy Aspirin Cardio without a prescription.