Levolet R tabs 500mg #10

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Levolet R instruction

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Antibacterial agent belonging to the fluoroquinolone group. The active element acts on a wide range of microorganisms. After taking the pill, its very rapid and maximum absorption from the gastrointestinal tract - organs is observed. Food has no effect on the effectiveness of Levolet R. It has been established that Levolet P is able to penetrate well enough into tissues and organs.

Release form and composition

The tablets of Levolet R have the main active ingredient in the form of levofloxacin hemihydrate. Each tablet is white or almost white, with a film coating; its shape is capsular and biconvex. The composition may contain 500 mg or 250 mg of levofloxacin. If a dosage of 250 mg is indicated, then on the side surfaces of the tablet there are the inscriptions "RDY" and "279". If the dosage of 500 mg is indicated, then on the side surfaces there are the inscriptions "RDY" and "280".
Auxiliary elements are indicated in the form of crospovidone, MCC, corn starch, hypromellose, colloidal silicon dioxide and magnesium stearate.
The film shell is made of opadry dye white OY 58900.
10 tablets placed in an aluminum blister, Levolet R is in a secondary cardboard container. There is 1 official instruction.

Indications for use

It is used in cases of infectious - inflammatory type in moderate or mild severity, which are triggered by microorganisms that are sensitive to the active element of tablets. It is prescribed in the presence of ENT - organ infections, prostatitis, infections of soft tissues or skin, lower respiratory tract diseases, intra-abdominal infections, bacteremia, pyelonephritis, urinary tract / kidney infections of uncomplicated and complicated type, septicemia. In the complex treatment possible therapy of tuberculosis forms that are resistant to medication drugs.


Contraindications for Levolet R

It is forbidden to use Levolet R during the lactation period, epilepsy, individual hypersensitivity (including quinolones), pregnancy, tendon lesions that developed after taking quinolones, as well as in children under the age of 18 years.
Caution is needed in the presence of older age or deficiency of glucose-6-phosphate dehydrogenase.

Dosing and Administration

It is necessary to take the tablet form of Levolet R before meals or in between meals. Chewing is not allowed. To wash down with a sufficient volume of liquid.
The dosage of Levolet R is selected by a specialist in an individual way.
In the normal functioning of the kidneys (or reduced slightly), the following schemes are recommended.
Sinusitis: course - 10 - 14 days. A single dose of 500 mg per day;
Exacerbation of bronchitis in chronic manifestations: a course of up to 2 weeks. Once a day, 250 to 500 mg;
Community-acquired pneumonia: a course of 1 to 2 weeks. Reception 1 or 2 times at 24 hours on 500 mg;
Uncomplicated urinary tract infections: a three-day course of 250 mg once a day;
Urinary tract infections of a complicated type (including pyelonephritis): a course of 7 to 10 days. Once per day, 250 mg;
Prostatitis: course - 28 days, 500 mg once a day in 24 hours;
Bacteremia / septicemia: a course of 10 to 14 days, 500 mg 1 or 2 times in 24 hours;
Intra-abdominal infection: course from 1 to 2 weeks. At 500 mg 1 time / day. Used complex treatment;
Infection of soft tissues or skin: a course - 1 or 2 weeks, 250 mg 1 - 2 times per 24 hours or once a day, 500 mg;
Sustainable tuberculosis forms: a course - up to 90 days on 500 - 1000 mg once a day.
Correction of dosages of Levolet R depending on the performance of clearance is carried out individually.
The introduction of additional doses after dialysis of permanent ambulatory peritoneal or hemodialysis is not necessary.
When violations in the liver functioning of the selection of special dosages is not performed.
Usually the treatment takes no more than 2 weeks.

Side effects of Levolet R

Often recorded cases of diarrhea, dysbiosis, changes in hepatic blood counts, nausea.
Sometimes there are cases of asthenia, reddening of the skin, itching of the skin, pain in the head, dizziness, sleep and digestive disorders, drowsiness, pain in the gastrointestinal tract - organs, loss of appetite, leukopenia, eosinophilia.
Rarely encountered: anaphylaxis, asphyxiation, tendon lesions, hypercreatininemia, restlessness, fear, convulsions, paresthesias in the hands, confused consciousness, a decrease in blood pressure, heartbeat, diarrhea with blood, changes in the clinical indicators of the patient's blood.
Shown very rare cases of superinfection resistant fever, photosensitivity, shock, anaphylactic, sharp fall in blood pressure indicators, muscle weakness, tendon rupture, renal failure, hypoglycemia, disturbances of sound and vision, smell sensitivity (tactile, gustatory), depression, motor disorders , hallucinations, vascular collapse, hepatitis, agranulocytosis.
In some cases: Lyell's syndrome, allergic pneumonitis, erythema multiforme exudative, Stevens-Johnson syndrome, vasculitis, rhabdomyolysis, exacerbation of porphyria, lengthening of the QT interval, pancytopenia, hemolytic anemia.


special instructions for Levolet R

Overdose is indicated by symptoms in the form of erosive lesions of the gastrointestinal tract - organs, nausea, confusion, lengthening of the QT interval, seizures, dizziness. In this case, dialysis is ineffective, symptomatic therapy.

Interactions

    increases T1 / 2 cyclosporine;
    means of inhibiting intestinal motility, antacids, sucralfate, preparations with salts of iron, magnesium, aluminum: a decrease in the complete absorption of levofloxacin;
    theophylline, NSAIDs - group: increase in convulsive readiness;
    GKS: probability of tendon rupture;
    substances that block tubular secretion and cimetidine: delayed clearance.
Lactation, pregnancy: Levolet R is contraindicated.
In order to reduce the risk of possible photosensitization, it is necessary to carefully avoid sunlight and artificial ultraviolet radiation during the treatment period.
If you experience allergic symptoms, signs of colitis pseudomembranous, tendonitis, tablets are immediately canceled.
The occurrence of seizures is likely in the presence of a history of GM lesions. The risk of hemolysis increases with glucose-6-phosphate dehydrogenase deficiency.
Care must be taken when driving personal vehicles and working with complex mechanisms.
With minor violations in the work of the kidneys dosage of Levolet R adjustment is not carried out, in other cases it is necessary.
At disturbances of the process of hepatic functioning, dose adjustment is not performed.
Under 18 years, the remedy is contraindicated.

Terms and conditions of storage

Places Levolet R with temperatures not higher than 25 degrees, inaccessible to children, dry, carefully protected from all light sources, are selected. Do not freeze. Carry out the storage process no more than 2 years, but not longer than the specified date on the container.

Terms of sell

You don't need a prescription to buy Levolet R.