Alfa Normix tabs 200mg #12

Alfa Normix instruction

You can buy Alfa Normix here

The substance belongs to the class of ansamycins and is a semisynthetic antibiotic. The component provides the main pharmacological properties of the drug and explains its high efficacy in the treatment of infectious diseases of the digestive tract.
Additionally, the drug removes toxic compounds from the body and suppresses the intensity of antigenic stimuli that provoke a persistent development of the inflammatory process. The resistance of bacteria to Alfa Normix in medical practice is found in isolated cases.
The dosage and duration of the course of taking Alfa Normix differ depending on the indications. A detailed scheme of the drug is explained by the manufacturer in the instructions. Only a doctor can adjust the treatment plan. The manual also contains information on pathologies in which the effectiveness of Alfa Normix reaches maximum performance, a list of contraindications and special instructions. Additionally, the manufacturer notes the nuances of drug interaction of the drug and possible side effects after taking it.

pharmachologic effect

Alfa Normix is ​​a drug known as a broad spectrum antibiotic. It is active against most gram-positive and gram-negative, anaerobic and aerobic bacteria that cause intestinal and stomach infections (including diarrhea "travelers").
The use of the drug helps to reduce the pathogenic intestinal bacterial load, which causes certain pathological conditions.
The drug reduces:
    the intensity of the antigenic stimulus that can constantly maintain or initiate chronic inflammation of the intestine;
    the presence of bacteria capable of participating in inflammation around and inside the diverticular sac) in the diverticulum of the colon;
    the formation of ammonia by bacteria, other toxic compounds that, in the case of severe liver ailments accompanied by impaired detoxification, are involved in the pathogenesis of hepatic encephalopathy;
    the risk of infectious complications during surgical / colorectal interventions;
    increased proliferation of microorganisms in the presence of overgrowth syndrome in the intestines of bacteria.

Indications for use

The drug Alfa Normix is ​​used to treat gastrointestinal infections caused by bacteria susceptible to rifaximin, incl. with:
    diarrhea "travelers";
    acute gastrointestinal infections;
    colitis, gastroenteritis;
    bacterial overgrowth syndrome in the intestine;
    hepatic encephalopathy;
    chronic intestinal inflammation;
    diverticular disease of the colon (symptomatic uncomplicated).
Also, the drug is used in colorectal surgery to prevent complications of infectious origin.

Mode of application

For the treatment of children older than 12 and adults prescribe: 1 tablet for every 8 hours or 2 tablets for every 8-12 hours (respectively, 600-1200 mg of rifaximin). The recommended duration of treatment is no more than 1 week. The duration of therapy is determined in private and depends on the clinical condition of the patient.
If necessary, the possibility of a second course of treatment is allowed. The interval between two courses should be at least 20-40 days. The frequency of taking the drug and its dose may be changed on the recommendation of the attending physician.

Release form, composition

The drug is available in the form of convex round tablets coated in pink. Each blister contains 12 tablets, each package is one or three blisters.
In addition, the drug is sold in the form of orange granules for the preparation of suspensions. The finished suspension has a characteristic cherry flavor and aroma. Granules are sold in 5 ml dark glass bottles. Measuring cup included.
1 tablet contains the active ingredient rifaximin (200 mg), additional components - microcrystalline cellulose, sodium carboxymethyl starch, glycerin palmitostearate, talc, colloidal silica, propylene glycol, hypromellose, titanium dioxide, E172, disodium edetate.

Interaction with other drugs

Information about the drug drug interactions with other drugs today are not available.
At the system level, drug interactions are unlikely due to poor systemic absorption (less than 1%).

Side effects of Alfa Normix

Hematopoietic system - thrombocytopenia, neutropenia, monocytosis, lymphocytosis.
Cardiovascular system - flushing of the face, feeling of heartbeat, increase in arterial pressure.
Metabolic dehydration disorders - loss of appetite.
Immune system - laryngeal edema, anaphylactic shock, hypersensitivity, anaphylactic reactions.
CNS - headaches, dizziness; pain in the sinus area, drowsiness, paresthesia, migraine, hypesthesia; excitement, faintness.
Mind nervousness, insomnia, depressive mood, pathological dreams.
Reactions: general swelling of the face, cold sweat, hyperhidrosis, asthenia, peripheral edema, painful sensations of uncertain localization, flu-like symptoms, chills; fever.
Urinary system - proteinuria, hematuria, polyuria, pollakiuria, glycosuria.
Subcutaneous fat, sunburn skin, rash; genital itching, erythema of the palms, erythematous rash, urticaria, purpura, pruritus, allergic dermatitis, erythema, angioedema, eczema, exfoliative dermatitis.
Digestive system - heartburn, altered functional liver tests; agevziya, increased AST activity, dry lips, impaired gastrointestinal motility, “hard” stools, abdominal pain (upper part), appearance of blood and mucus in the feces, dyspepsia, ascites; urging to defecate flatulence, abdominal distension, vomiting, constipation, tenesmus, abdominal pain, nausea, diarrhea.

Overdose

At observance of the dosages specified in the instruction to Alfa Normix, the risk of overdose is completely excluded. Side effects of overdose can be indicated by wandering pains in the area of ​​the digestive organs, excessive drowsiness and fatigue, as well as other conditions indicated in the corresponding paragraph of the instruction. Severe effects are excluded (Alfa Normix is practically not absorbed into the systemic circulation).
Possible consequences of overdose:
    shortness of breath, headache, and high blood pressure;
    nausea combined with pain in the epigastric region;
    heartburn and taste disturbance;
    Quincke swelling.

Contraindications

The drug Alfa Normix prohibited from taking with:
    intestinal obstruction (including partial);
    hypersensitivity to the drug;
    defeat intestinal severe ulcers;
    hypersensitivity to rifaximin or other rifamycins;
    children age (less than 12 years).

During pregnancy

During lactation (during lactation), pregnancy, the use of Alfa Normix is ​​possible only in case of urgent need and under medical supervision.

special instructions

Influence on ability of driving of motor transport and management of mechanisms

Side effects of Alfa Normix include drowsiness, headache, and dizziness. In the event of such conditions, the control of dangerous mechanisms must be abandoned. With the right drug intake and the absence of adverse symptoms, there are no violations of psychomotor reactions.

Pregnancy and lactation

It is strictly forbidden to take Alfa Normix during pregnancy. The antibiotic can not only penetrate the placenta, but also have a negative effect on the process of formation of the fetal skeleton. A similar ban applies to the period of breastfeeding (lactation can be resumed after a certain period of time after therapy and with full recovery of the woman).

Use in childhood

Treatment by Alfa Normix is ​​allowed only when the child reaches two years of age.

In case of impaired renal function

Information about the need to adjust the course of therapy or dosages in the instructions is missing. The drug is used according to the standard scheme recommended by the manufacturer.

With abnormal liver function

Hepatic encephalopathy is a indication for prescribing Alfa Normix. Special instructions for taking the drug in other pathologies of the liver in the instructions are not contained.

Terms and conditions of storage

Keep out of reach of children at temperature up to 30 ° С. The drug is valid for 3 years from the date of issue.

Reviews

Reviews of antibiotics are mostly positive. It can be used for the treatment of chronic intestinal diseases and as an emergency remedy. Patients note that Alfa Normix is a fairly strong antibiotic. At the end of the course of treatment, it is recommended to take a course of probiotics, which will allow the normal microflora to be restored in the intestine.

Total

    Damage to the intestinal mucosa and prolonged treatment in high doses - all this can cause a slight absorption of the drug and staining in the reddish color of urine.
    The antibiotic can be taken both after and before meals (regardless of the meal).
    With the development of superinfection microorganisms insensitive to rifaximin, it is necessary to stop taking the drug, and also to prescribe the appropriate therapy.
    Alfa Normix is ​​positioned as an antibiotic with a wide spectrum of activity. The drug is distinguished by a fairly high price and effectiveness, which is not inferior to other drugs of its group. From pharmacies Alfa Normix released by prescription.

Terms of sell

You don't need a prescription to buy Alfa Normix.